Evidence map›Paper›PMID 26423242›Full record

ArticleBMC cardiovascular disorders2015

Elevated resting heart rate predisposes metabolic syndrome in women rather than in men: a 15-year prospective study.

Si Wang, Kai Liu, Xin Zhang, Qingtao Meng, Yong Wang, Shixi Wan, Xiaoping Chen

Open access · goldAbstract read
In one paragraph

Article in BMC cardiovascular disorders, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Si WangDepartment of Cardiovascular Medicine, West China Hospital, Sichuan University, Chengdu, 610041, China. 27880114@qq.com.
Kai LiuDepartment of Cardiovascular Medicine, West China Hospital, Sichuan University, Chengdu, 610041, China. 297300058@qq.com.
Xin ZhangDepartment of Cardiovascular Medicine, West China Hospital, Sichuan University, Chengdu, 610041, China. soszhangxin@163.com.
Qingtao MengDepartment of Cardiovascular Medicine, West China Hospital, Sichuan University, Chengdu, 610041, China. 309225245@qq.com.
Yong WangDepartment of Cardiovascular Medicine, West China Hospital, Sichuan University, Chengdu, 610041, China. 840771563@qq.com.
Shixi WanDepartment of Cardiovascular Medicine, West China Hospital, Sichuan University, Chengdu, 610041, China. 455917695@qq.com.
Xiaoping ChenDepartment of Cardiovascular Medicine, West China Hospital, Sichuan University, Chengdu, 610041, China. xiaopingchen11@126.com.
West China Hospital of Sichuan University · CNSichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIncreasing evidences have indicated that there are gender differences in the prevalence of metabolic syndrome(MS), but the mechanism is uncertain.

methodsA total of 711 subjects aged 35-65 years accepted health examinations both in 1992 and 2007. Since 114 subjects had MS and 7 had heart disease at baseline, they were excluded from the analysis. Therefore, 590 subjects with complete data (male: 61.5 %) were available and analysed. After the relationship between gender and incident MS at follow-up was tested, these subjects were categorized into four groups according to the baseline resting heart rate(RHR) classified by genders. Trend tests of MS incidences across the four groups of resting heart rate were conducted by Cochran-Armitage tend tests in both men and women. Additionally, three logistic regression models were used to estimate the effects of RHR on the new onset of MS by taking RHR as a continuous variable(per 4 beats/min elevation).

resultsGender(women) itself was an independent risk factor for incident MS at follow-up(OR = 2.64, 1.33-5.23, P = 0.005). The incidences of MS according to the RHR categories showed a statistical linear trend in women(P for trend = 0.018) rather than in men(P for trend = 0.194). The ORs[95 % confidence intervals(CIs)] of MS for each 4 bpm elevation in RHR was 1.18(1.03-1.36)(P = 0.020) in a univariate model, 1.20 (1.04-1.38) (P = 0.011) adjusted for age and health related behaviors only and 1.23(1.06-1.43)(P = 0.007) adjusted for age, health related behaviors and pre-existing components of MS in the baseline in women. Otherwise, RHR did not have any significant associations with incident MS in men neither in a univariate model nor in multivariate models.

conclusionsIn this study, elevated RHR is correlated with the development of MS in women rather than in men.

Indexed as

Heart RateAdultAgedFemaleFollow-Up StudiesHealth BehaviorHumansIncidenceMaleMetabolic SyndromeMiddle AgedProspective StudiesRisk FactorsSex Factors

Identifiers

PMID26423242
PMCPMC4590309
OpenAlexW2096195620

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.