ArticleDigestive diseases and sciences2016
Morphological Characteristics of Early Gastric Neoplasms Detected After Helicobacter pylori Eradication.
Article in Digestive diseases and sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed, 20 citations in OpenAlex.
- Advanced Gastric Cancer Presenting as a Giant Subepithelial Lesion: A Case Report.Clinical case reports · 2026Article
- Gastric Cancer after <italic>Helicobacter pylori</italic> Eradication: Characteristics, Diagnosis, and Management.Digestion · 2025Review
- A novel color-aided system for diagnosis of early gastric cancer using magnifying endoscopy with narrow-band imaging.Surgical endoscopy · 2024Article
- Research progress on molecular mechanism of pyroptosis caused byAnnals of medicine and surgery (2012) · 2024Review
- [Approach to Patients after Successful Eradication ofThe Korean journal of helicobacter and upper gastrointestinal research · 2023Review
- Endoscopic characteristics and high-risk background mucosa factors of early gastric cancer after helicobacter pylori eradication: a single-center retrospective study.Frontiers in oncology · 2023Article
- Characteristics and background mucosa status of early gastric cancer after Helicobacter pylori eradication: A narrative review.Medicine · 2022Review
- Advanced gastric cancer detected during regular follow-up after eradication of Helicobacter pylori.Clinical journal of gastroenterology · 2022Article
- Effect of Helicobacter pylori infection on malignancy of undifferentiated-type gastric cancer.BMC gastroenterology · 2022Article
- Review
- Characteristics and Early Diagnosis of Gastric Cancer Discovered afterGut and liver · 2021Review
- Fluorescence detection of deep intramucosal cancer excited by green light for photodynamic diagnosis using protoporphyrin IX induced by 5-aminolevulinic acid: an ex vivo study.Journal of biomedical optics · 2020Article
- Genomic landscape of epithelium with low-grade atypia on gastric cancer after Helicobacter pylori eradiation therapy.Journal of gastroenterology · 2019Article
- Objective image analysis of non-magnifying image-enhanced endoscopy for diagnosis of small depressed early gastric cancers.Endoscopy international open · 2018Article
- Characteristics and predictors of gastric cancer afterWorld journal of gastroenterology · 2018Review
- Endoscopic Detection of Gastric Carcinoma After Helicobacter pylori Eradication: More Difficult or Just Hype?Digestive diseases and sciences · 2016Article
- Development and Validation of an Individualized Nomogram to Identify Undifferentiated-Predominant Mixed-Type Early Gastric Cancer.Journal of digestive diseasesObservational
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12 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundPrevious morphological studies indicated that the eradication of Helicobacter pylori (H. pylori) made gastric neoplasms endoscopically indistinct through the flattening and covering of tumors with a non-neoplastic epithelium (NE).
aimTo validate these alterations.
methodsWe reviewed and compared the endoscopic and histological findings of early gastric carcinomas and high-grade dysplasias resected endoscopically from H. pylori-infected and H. pylori-eradicated patients. The extent of NE covering a tumor was expressed as the histological length ratio of NE to the tumor. Tumor morphology was compared before and after therapies in patients who received H. pylori eradication treatments during the period from tumor discovery to endoscopic resection.
resultsNE-covered ratios were higher in the 59 tumors detected after the eradication of H. pylori than in the 152 tumors detected during the infection (median 8 vs. 0 %, respectively), whereas the frequency at which an elevated morphology and whitish discoloration of a tumor were observed was less (14 vs. 56 %, and 14 vs. 43 %, respectively). These were also independent characteristics for tumors detected after the eradication of H. pylori. Two elevated tumors showing whitish discoloration out of 16 tumors became endoscopically indistinct following H. pylori eradication treatments through the flattening of tumors and muting of the discoloration.
conclusionThe eradication of H. pylori promoted covering with NE, the flattening of tumors, and muting of the whitish discoloration, which may make a subset of tumors, potentially including whitish elevated neoplasms, indistinct.
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