ArticleDepression and anxiety2016
ANXIOUS AND AGGRESSIVE: THE CO-OCCURRENCE OF IED WITH ANXIETY DISORDERS.
Article in Depression and anxiety, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed, 37 citations in OpenAlex.
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- Vasopressin 1a Receptor Antagonists for Pathological Aggression in Neurodegenerative and Other CNS Diseases.Biomedicines · 2026Review
- Medial preoptic CCKAR mediates anxiety and aggression induced by chronic emotional stress in male mice.National science review · 2025Article
- Turkish Adaptation of the Screening Questionnaire for Intermittent Explosive Disorder.Alpha psychiatry · 2025Article
- Dissecting different forms of impulsivity and its relationships to anxiety in the link between alcohol dependence and aggression among Chinese male alcohol-dependent patients.SAGE open medicine · 2025Article
- Adult ADHD and comorbid anxiety and depressive disorders: a review of etiology and treatment.Frontiers in psychiatry · 2025Review
- The Relationship Between Specific Adult Attention-Deficit/Hyperactivity Disorder Symptoms and Anxiety Using Self-Report Diagnostic Scales.Journal of the Korean Academy of Child and Adolescent Psychiatry · 2024Article
- Cognitive Flexibility and Emotion Regulation in Eating Disorder Patients with Comorbid Generalized Anxiety and Posttraumatic Stress Symptoms.Research square · 2024Article
- Hostile and threatening interpretation biases in adolescent inpatients are specific to callous-unemotional traits and social anxiety.European child & adolescent psychiatry · 2024Article
- The role played by government communication on the level of public fear in social media: An investigation into the Covid-19 crisis in Italy.Government information quarterly · 2023Article
- Tetratricopeptide repeat domain 9A knockout induces social anxiety and impairs offense behaviors in female mice.Iranian journal of basic medical sciences · 2022Article
- Psychiatric comorbidity in Intermittent Explosive Disorder.Journal of psychiatric research · 2019Article
- The co-occurrence and correlates of anxiety disorders among adolescents with intermittent explosive disorder.Aggressive behavior · 2018Article
- Social Learning Requires Plasticity Enhanced by Fluoxetine Through Prefrontal Bdnf-TrkB Signaling to Limit Aggression Induced by Post-Weaning Social Isolation.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2018Article
- Irritability in Youths: A Translational Model.The American journal of psychiatry · 2017Review
- Phenotypic factor analysis of psychopathology reveals a new body-related transdiagnostic factor.PloS one · 2017Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundEvidence suggests that impulsive aggression and explosive anger are common among individuals with anxiety disorders; yet, the influence of intermittent explosive disorder (IED) on the onset, course, consequences, and patterns of comorbidity among those with anxiety disorders is unknown.
methodsData were drawn from the National Comorbidity Survey Replication (N = 9,282) and Adolescent Supplement (N = 9,632), nationally representative surveys conducted between 2001 and 2004. Diagnoses were based on structured lay-administered interviews. Lifetime diagnoses were assessed with structured instruments. Outcomes included comorbidity, functional and role impairment, and treatment utilization.
resultsAdolescents with a lifetime anxiety disorder had a higher prevalence of a lifetime anger attacks (68.5%) and IED (22.9%) than adolescents without a lifetime anxiety disorder (48.6 and 7.8%, respectively), especially social phobia and panic disorders. Similar elevation was found for adults. Age of onset and course of anxiety disorders did not differ by IED. Severe functional impairment associated with anxiety was higher among adolescents (39.3%) and adults (45.7%) with IED than those without IED (29.2 and 28.2%, respectively). Comorbidity for all other disorders was elevated. However, individuals with anxiety disorders and IED were no more likely to use treatment services than those with anxiety disorders without IED.
conclusionsIndividuals with IED concomitant to anxiety disorder, especially social phobia and panic, are at marked risk for worse functional impairment and a higher burden of comorbidity, but onset and course of anxiety disorder do not differ, and those with anxiety and IED are no more likely to utilize treatment services. Assessment, identification, and specialized treatment of anger in the context of anxiety disorders are critical to reducing burden.
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