ArticlePloS one2015
The Association of Maternal Lifestyle with Birth Defects in Shaanxi Province, Northwest China.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
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Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Prevalence and associated factors of congenital anomalies in Ethiopia: A systematic review and meta-analysis.PloS one · 2024Pooled it
- Prevalence of Orofacial Clefts among Live Births in China: A Systematic Review and Meta-Analysis.Birth defects research · 2017Pooled it
- Season, household registry and isolated birth defects: a population-based case-control study in Danyang, China.International health · 2024Article
- Prevalence and Trends of Birth Defects - Five Counties, Shanxi Province, China, 2003-2022.China CDC weekly · 2023Article
- Association between usage of household cooking fuel and congenital birth defects-18 months multi-centric cohort study in Nepal.Archives of public health = Archives belges de sante publique · 2023Article
- Birth Defects Associated with Prenatal Alcohol Exposure-A Review.Children (Basel, Switzerland) · 2023Review
- Article
- Initial study on quantitative electroencephalographic analysis of bioelectrical activity of the brain of children with fetal alcohol spectrum disorders (FASD) without epilepsy.Scientific reports · 2023Article
- Risk Assessment for Birth Defects in Offspring of Chinese Pregnant Women.International journal of environmental research and public health · 2022Article
- Caffeine use during pregnancy: prevalence of use and newborn consequences in a cohort of French pregnant women.European archives of psychiatry and clinical neuroscience · 2021Article
- Association between maternal iron supplementation and newborn birth weight: a quantile regression analysis.Italian journal of pediatrics · 2021Article
- Association of Short and Long Interpregnancy Intervals with Adverse Birth Outcomes: Evidence from a Cross-Sectional Study in Northwest China.International journal of general medicine · 2021Article
- Maternal health behaviors during pregnancy in rural Northwestern China.BMC pregnancy and childbirth · 2020Article
- Major birth defects in the Brazilian side of the triple border: a population-based cross-sectional study.Archives of public health = Archives belges de sante publique · 2020Article
- Article
- Observational
- Prevalence of non-syndromic orofacial clefts: based on 15,094,978 Chinese perinatal infants.Oncotarget · 2018Article
- Prevalence of Oral Clefts among Live Births in Gansu Province, China.International journal of environmental research and public health · 2018Article
- Socioeconomic inequalities and determinants of maternal health services in Shaanxi Province, Western China.PloS one · 2018Article
- Using latent class cluster analysis to screen high risk clusters of birth defects between 2009 and 2013 in Northwest China.Scientific reports · 2017Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe main objective was to investigate the burden of birth defects among alive infants and explore the impact of maternal lifestyle during pregnancy on the burden of birth defects in Northwest China.
methodsA stratified multi-stage sampling method was used to study infants born during 2010-2013 (and their mothers) in Shaanxi province of Northwest China. Socio-demographic information was collected using a structured questionnaire, and medical records from the local hospitals were used to determine the final diagnosis of birth defects. Poisson regression analysis was performed to assess the association between maternal lifestyles during pregnancy and the burden of birth defects, while adjusting for potential confounders.
resultsWe sampled 29098 infants, of whom 629 (i.e. 216.17 per 10000) were observed to have congenital defects. Cardiovascular system defects (77.32 per 10000) were found to be the most common. Mothers who had ever consumed alcohol during pregnancy were found to have infants with a higher prevalence of some categories of birth defects, including nervous system (Prevalence Rate Ratio, PRR:14.67, 95% CI: 1.94, 110.92), cardiovascular system (PRR:3.22, 95% CI: 1.02, 10.16) and oral clefts (PRR:9.02, 95% CI: 2.08, 39.10) in contrast to infants of mothers without any alcohol consumption. Maternal passive smoking during pregnancy lead to the increased burden of malformations of eye, ear, face and neck (PRR:1.95, 95% CI: 1.15, 3.33), cardiovascular system (PRR:1.70, 95% CI: 1.25, 2.31) and respiratory system (PRR:9.94, 95% CI: 2.37, 41.76) in their newborns. Further, tea or coffee consumption during pregnancy was positively correlated with the burden of specific birth defects, such as cardiovascular system (PRR: 2.44, 95% CI: 1.33, 4.46) and genital organs (PRR:14.72, 95% CI: 1.87, 116.11) among infants.
conclusionsThe prevalence of birth defects was high in Shaanxi province of Northwest China. The unhealthy lifestyles of mothers during pregnancy may increase the prevalence of congenital malformations. These findings in future may have some important implications for prevention of birth defects in Northwest China.
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