Evidence map›Paper›PMID 26422474›Full record

ArticlePloS one2015

High Treatment Retention Rate in HIV-Infected Patients Receiving Antiretroviral Therapy at Two Large HIV Clinics in Hanoi, Vietnam.

Shoko Matsumoto, Junko Tanuma, Daisuke Mizushima, Ngoc Chi Thi Nguyen, Thanh Thuy Thi Pham, Cuong Duy Do, Tuan Quang Nguyen, Dung Thi Nguyen, Hoai Dung Thi Nguyen, Lam Tien Nguyen and 2 more

Abstract read
In one paragraph

Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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  7. Cryptococcal meningitis: A neglected NTD?PLoS neglected tropical diseases · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Shoko MatsumotoAIDS Clinical Center, National Center for Global Health and Medicine, Tokyo, Japan; Graduate School of Public Health, Teikyo University, Tokyo, Japan.
Junko TanumaAIDS Clinical Center, National Center for Global Health and Medicine, Tokyo, Japan.
Daisuke MizushimaAIDS Clinical Center, National Center for Global Health and Medicine, Tokyo, Japan; Center for AIDS Research, Kumamoto University, Kumamoto, Japan.
Ngoc Chi Thi NguyenDepartment of Infectious Diseases, Bach Mai Hospital, Hanoi, Vietnam.
Thanh Thuy Thi PhamDepartment of Infectious Diseases, Bach Mai Hospital, Hanoi, Vietnam.
Cuong Duy DoDepartment of Infectious Diseases, Bach Mai Hospital, Hanoi, Vietnam.
Tuan Quang NguyenDepartment of Infectious Diseases, Bach Mai Hospital, Hanoi, Vietnam.
Dung Thi NguyenNational Hospital of Tropical Diseases, Hanoi, Vietnam.
Hoai Dung Thi NguyenNational Hospital of Tropical Diseases, Hanoi, Vietnam.
Lam Tien NguyenNational Hospital of Tropical Diseases, Hanoi, Vietnam.
Kinh Van NguyenNational Hospital of Tropical Diseases, Hanoi, Vietnam.
Shinichi OkaAIDS Clinical Center, National Center for Global Health and Medicine, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLoss to follow-up (LTFU) is viewed as a major challenge in improving retention in HIV treatment. In Vietnam, the reasons for disengagement from clinics and the effect of injection drug use (IDU) on LTFU with unknown outcome (true LTFU) are not well known.

methodsPatients receiving antiretroviral therapy (ART) from two HIV clinics in Hanoi were included in this observational study between 2007 and 2012, and followed up every 6 months until the end of 2013. The reasons for disengagement from the clinic, and ART status during imprisonment were investigated in patients with a history of IDU to identify true LTFU. The retention rate at 6-54 months and true LTFU rate were calculated. Cox proportional hazards regression models were performed to identify factors associated with true LTFU.

resultsThere were 1,431 patients, with a follow-up time of 4,371 person-years (median 2.49 years). At the end of the follow-up period, 71 (5.0%) patients died, 79 (5.5%) transferred to other clinics, 16 (1.1%) disengaged from the clinics, and the calculated true LTFU was 45 (3.1%), with 12-month ART retention rate of 95.3% for the entire study population. Imprisonment was the most frequent reason for disengagement from the clinics. True LTFU correlated significantly with low CD4 count and high plasma viral load, but not history of IDU.

conclusionImprisonment is a major cause of disengagement from HIV care among patients with a history of IDU.

Indexed as

Outcome Assessment, Health CareAdolescentAdultAgedAged, 80 and overAnti-HIV AgentsFemaleHIV InfectionsHumansMaleMiddle AgedVietnamYoung AdultAnti-HIV Agents

Identifiers

PMID26422474
PMCPMC4589350

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.