ArticleOrganic letters2015
Small Molecules in the Cone Snail Arsenal.
Article in Organic letters, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- Pooled it
- Unveiling Diversity and Function: Venom-Associated Microbes in Two Spiders, Heteropoda venatoria and Chilobrachys guangxiensis.Microbial ecology · 2024Article
- The Sobering Sting: Oleoyl Serotonin Is a NovelBiomedicines · 2024Article
- Predatory and Defensive Strategies in Cone Snails.Toxins · 2024Review
- Cone snail species off the Brazilian coast and their venoms: a review and update.The journal of venomous animals and toxins including tropical diseases · 2023Review
- Article
- Comparative Venomics of the Cryptic Cone Snail SpeciesMarine drugs · 2022Article
- Biomedical Potential of the Neglected Molluscivorous and VermivorousMarine drugs · 2022Review
- Article
- Targeting SARS-CoV-2 Polymerase with New Nucleoside Analogues.Molecules (Basel, Switzerland) · 2021Article
- Small-molecule mimicry hunting strategy in the imperial cone snail,Science advances · 2021Article
- Non-Peptidic Small Molecule Components from Cone Snail Venoms.Frontiers in pharmacology · 2021Review
- Curses or Cures: A Review of the Numerous Benefits Versus the Biosecurity Concerns of Conotoxin Research.Biomedicines · 2020Review
- RgIA4 Accelerates Recovery from Paclitaxel-Induced Neuropathic Pain in Rats.Marine drugs · 2019Article
- Marine Alkylpurines: A Promising Group of Bioactive Marine Natural Products.Marine drugs · 2018Review
- Three New Cytotoxic Steroidal Glycosides Isolated from Conus pulicarius Collected in Kosrae, Micronesia.Marine drugs · 2017Article
- Stenotrophomonas-Like Bacteria Are Widespread Symbionts in Cone Snail Venom Ducts.Applied and environmental microbiology · 2017Article
- Linking neuroethology to the chemical biology of natural products: interactions between cone snails and their fish prey, a case study.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2017Review
- Small Packages, Big Returns: Uncovering the Venom Diversity of Small Invertebrate Conoidean Snails.Integrative and comparative biology · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
Abstract
Cone snails are renowned for producing peptide-based venom, containing conopeptides and conotoxins, to capture their prey. A novel small-molecule guanine derivative with unprecedented features, genuanine, was isolated from the venom of two cone snail species. Genuanine causes paralysis in mice, indicating that small molecules and not just polypeptides may contribute to the activity of cone snail venom.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.