Evidence map›Paper›PMID 26421314›Full record

ReviewTheScientificWorldJournal2015

Biological Events in Periodontal Ligament and Alveolar Bone Associated with Application of Orthodontic Forces.

L Feller, R A G Khammissa, I Schechter, G Thomadakis, J Fourie, J Lemmer

Open access · goldAbstract readReview
In one paragraph

Review in TheScientificWorldJournal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 67 citations in OpenAlex.

  1. Trial
  2. Article
  3. Mechanical control in dental and jaw morphogenesis and remodeling.International journal of oral science · 2026
    Review
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  20. Biomaterials and biotechnology for periodontal tissue regeneration: Recent advances and perspectives.Journal of dental research, dental clinics, dental prospects · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

L FellerDepartment of Periodontology and Oral Medicine, Sefako Makgatho Health Sciences University, Pretoria 0204, South Africa.
R A G KhammissaDepartment of Periodontology and Oral Medicine, Sefako Makgatho Health Sciences University, Pretoria 0204, South Africa.
I SchechterSchulich Faculty of Chemistry, Technion-Israel Institute of Technology, 32000 Haifa, Israel.
G ThomadakisPrivate Practice, 15 School Road, Morningside, Johannesburg 2057, South Africa.
J FourieDepartment of Periodontology and Oral Medicine, Sefako Makgatho Health Sciences University, Pretoria 0204, South Africa.
J LemmerDepartment of Periodontology and Oral Medicine, Sefako Makgatho Health Sciences University, Pretoria 0204, South Africa.
Sefako Makgatho Health Sciences University · ZATechnion – Israel Institute of Technology · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Orthodontic force-induced stresses cause dynamic alterations within the extracellular matrix and within the cytoskeleton of cells in the periodontal ligament and alveolar bone, mediating bone remodelling, ultimately enabling orthodontic tooth movement. In the periodontal ligament and alveolar bone, the mechanically induced tensile strains upregulate the expression of osteogenic genes resulting in bone formation, while mechanically induced compressive strains mediate predominantly catabolic tissue changes and bone resorption. In this review article we summarize some of the currently known biological events occurring in the periodontal ligament and in the alveolar bone in response to application of orthodontic forces and how these facilitate tooth movement.

Indexed as

Orthodontic WiresAlveolar Processbeta CateninBone RemodelingBone ResorptionGene Expression RegulationHumansOsteoclastsOsteogenesisPeriodontal LigamentSignal TransductionStress, MechanicalTensile StrengthTooth Movement TechniquesWnt Proteinsbeta CateninCTNNB1 protein, humanWnt Proteins

Identifiers

PMID26421314
PMCPMC4572431
OpenAlexW1649357419

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.