Evidence map›Paper›PMID 26421271›Full record

ArticleEmerging microbes & infections2015

Only a subset of C. canimorsus strains is dangerous for humans.

Francesco Renzi, Melanie Dol, Alice Raymackers, Pablo Manfredi, Guy Richard Cornelis

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Emerging microbes & infections, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Infective Endocarditis byMedicina (Kaunas, Lithuania) · 2024
    Review
  3. Article
  4. Article
  5. Article
  6. Cellulitis and transient bacteremia byAccess microbiology · 2022
    Article
  7. Capnocytophaga zoonotic infections: a 10-year retrospective study (the French CANCAN study).European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2022
    Observational
  8. Article
  9. Review
  10. Septic shock caused by Capnocytophaga canis after a cat scratch.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2020
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Genomic analysis reveals the presence of a class D beta-lactamase with broad substrate specificity in animal bite associated Capnocytophaga species.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2017
    Article
  16. Article
  17. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Francesco RenziDépartement de Biologie, Université de Namur , 5000 Namur, Belgium.
Melanie DolDépartement de Biologie, Université de Namur , 5000 Namur, Belgium.
Alice RaymackersDépartement de Biologie, Université de Namur , 5000 Namur, Belgium.
Pablo ManfrediBiozentrum der Universität Basel , CH-4056 Basel, Switzerland.
Guy Richard CornelisDépartement de Biologie, Université de Namur , 5000 Namur, Belgium ; Biozentrum der Universität Basel , CH-4056 Basel, Switzerland.
University of Namur · BEUniversity of Basel · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Capnocytophaga canimorsus are gram-negative bacteria living as commensals in the mouth of dogs and cats. C. canimorsus cause rare but life-threatening generalized infections in humans that have been in contact with a dog or a cat. Over the last years we collected 105 C. canimorsus strains from different geographical origins and from severe human infections or healthy dogs. All these strains were analyzed by 16S rDNA sequencing and a phylogenetic tree revealed two main groups of bacteria instead of one with no relation to the geographical origin. This branching was confirmed by the whole-genome sequencing of 10 strains, supporting the evidence of a new Capnocytophaga species in dogs. Interestingly, 19 out of 19 C. canimorsus strains isolated from human infections belonged to the same species. Furthermore, most strains from this species could grow in heat-inactivated human serum (HIHS) (40/46 tested), deglycosylate IgM (48/66) and were cytochrome-oxidase positive (60/66) while most strains from the other species could not grow in HIHS (22/23 tested), could not deglycosylate IgM (33/34) and were cytochrome-oxidase negative (33/34). Here, we propose to call Capnocytophaga canis (Latin: dog) the novel, presumably less virulent dog-hosted Capnocytophaga species and to keep the name C. canimorsus for the species including human pathogens.

Indexed as

AnimalsCapnocytophagaCatsConsensus SequenceDNA, RibosomalDog DiseasesDogsElectron Transport Complex IVGenome, BacterialGenome-Wide Association StudyGram-Negative Bacterial InfectionsHumansImmunoglobulin MPhylogenyPolymerase Chain ReactionPolysaccharidesDNA, RibosomalElectron Transport Complex IVImmunoglobulin MPolysaccharidesRNA, Ribosomal, 16SANIbacterial taxonomycommensalismgenome comparisonpathogenesis

Identifiers

PMID26421271
PMCPMC4576167
OpenAlexW2215435246

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.