Evidence map›Paper›PMID 26421089›Full record

ArticleJournal of medical devices2015

An On-Site Thermoelectric Cooling Device for Cryotherapy and Control of Skin Blood Flow.

Natalia Mejia, Karl Dedow, Lindsey Nguy, Patrick Sullivan, Sepideh Khoshnevis, Kenneth R Diller

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of medical devices, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Heat Transfer in Health and Healing.Journal of heat transfer · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Natalia MejiaDepartment of Biomedical Engineering, The University of Texas at Austin, 107 West Dean Keeton Street, Austin, TX 78712-1081 e-mail:  nathysmejia@utexas.edu.
Karl DedowDepartment of Biomedical Engineering, The University of Texas at Austin, 107 West Dean Keeton Street, Austin, TX 78712-1081 e-mail:  kdedow@gmail.com.
Lindsey NguyDepartment of Biomedical Engineering, The University of Texas at Austin, 107 West Dean Keeton Street, Austin, TX 78712-1081 e-mail:  lindseynguy@gmail.com.
Patrick SullivanDepartment of Biomedical Engineering, The University of Texas at Austin, 107 West Dean Keeton Street, Austin, TX 78712-1081 e-mail:  Psullivan000@gmail.com.
Sepideh KhoshnevisDepartment of Biomedical Engineering, The University of Texas at Austin, 107 West Dean Keeton Street, Austin, TX 78712-1081 e-mail:  sepideh@utexas.edu.
Kenneth R DillerFellow ASME Department of Biomedical Engineering, The University of Texas at Austin, 107 West Dean Keeton Street, Austin, TX 78712-1081 e-mail:  kdiller@mail.utexas.edu.

Funding

Devices and Methods to Obviate the Risk of Ischemic Injury during CryotherapyR01EB015522 · NIBIB · UNIVERSITY OF TEXAS AT AUSTIN · PI BROTHERS, ROBERT MATTHEW, DILLER, KENNETH R. · 2013 to 2016
$1.5M
NIBIB NIH HHS R01 EB015522
6 · The paper itself

Abstract

Cryotherapy involves the surface application of low temperatures to enhance the healing of soft tissue injuries. Typical devices embody a remote source of chilled water that is pumped through a circulation bladder placed on the treatment site. In contrast, the present device uses thermoelectric refrigeration modules to bring the cooling source directly to the tissue to be treated, thereby achieving significant improvements in control of therapeutic temperature while having a reduced size and weight. A prototype system was applied to test an oscillating cooling and heating protocol for efficacy in regulating skin blood perfusion in the treatment area. Data on 12 human subjects indicate that thermoelectric coolers (TECs) delivered significant and sustainable changes in perfusion for both heating (increase by (±SE) 173.0 ± 66.0%, P < 0.005) and cooling (decrease by (±SE) 57.7 ± 4.2%, P < 0.0005), thus supporting the feasibility of a TEC-based device for cryotherapy with local temperature regulation.

Indexed as

cryotherapyin situ coolingoscillating cooling and heatingskin blood perfusionthermoelectric cooling (TEC) module

Identifiers

PMID26421089
PMCPMC4574863

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.