ReviewJournal of oncology2015
Gallbladder Cancer in the 21st Century.
Review in Journal of oncology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 150 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
150 citing papers in PubMed, 3 syntheses or guidelines pooled it, 298 citations in OpenAlex.
- Paraneoplastic Syndromes in Gallbladder Cancer: A Systematic Review.Medicina (Kaunas, Lithuania) · 2025Pooled it
- Safety and cost of selective histopathological analysis for detecting cancer in surgical specimens: a systematic review.ANZ journal of surgeryPooled it
- Mixed Adenoneuroendocrine Carcinoma (MANEC) of the Gallbladder: A Systematic Review of Outcomes Following Surgical Management.In vivo (Athens, Greece)Pooled it
- Role of Endoscopic Ultrasonography in Management of Pancreaticobiliary Cancers: Recent Trends and Advances.Cancers · 2026Review
- Geographic and genetic diversity in gallbladder cancer mutation profiles: insights from a worldwide exome analysis.EBioMedicine · 2026Article
- A novel model based on apparent diffusion coefficient and signal intensity on MRI to quantify subtle internal difference between tumor-adjacent and -distant liver tissues in TBMC medical imaging · 2026Article
- Emergence of Liquid Biopsy in Precision Oncology: A Review of its diagnostic, Predictive and Therapeutic Applications in Gallbladder Cancer.Journal of gastrointestinal cancer · 2026Review
- Molecular insights into HER2/ERBB2 amplification and carcinogenesis in gallbladder cancer associated with pancreaticobiliary maljunction.Journal of gastroenterology · 2026Article
- Extended versus simple cholecystectomy in stage I gallbladder cancer: a SEER-based competing risk analysis with external validation.World journal of surgical oncology · 2025Article
- Adenocarcinoma of the gallbladder: an incidental histopathological finding post-operative laparoscopic cholecystectomy in Saudi Arabia.Journal of medicine and life · 2025Article
- Point-of-Care Testing and Biomarkers in Biliary Diseases: Current Evidence and Future Directions.Journal of clinical medicine · 2025Review
- Gallbladder Squamous Cell Carcinoma with Diffuse β-hCG Expression: A Case Report and Review of the Literature.Journal of gastrointestinal cancer · 2025Review
- Gallbladder Carcinoma in a Eurasian Otter (Animals : an open access journal from MDPI · 2025Article
- Data Resource Profile: EULAT Eradicate GBC: the European-Latin American Research Consortium towards Eradication of Preventable Gallbladder Cancer.International journal of epidemiology · 2025Article
- MDM2 as a therapeutic target in advanced biliary tract cancers.The oncologist · 2025Review
- Enumeration, classification and clinical application of circulating tumor cells in advanced gallbladder adenocarcinoma.BMC cancer · 2025Article
- Perforated Calculous Cholecystitis and Incidental Squamous Cell Carcinoma of the Gallbladder-A Complex Relationship with a Difficult Management in the Acute Setting.Medicina (Kaunas, Lithuania) · 2025Article
- Article
- Clinical Study on the Combined Application of Ultrasound Probes to Improve the Diagnostic Value of Adenomyosis at the Bottom of the Gallbladder.Journal of multidisciplinary healthcare · 2025Article
- Establishment of a chronic biliary disease mouse model with cholecystoduodenal anastomosis for intestinal microbiome preservation.World journal of gastroenterology · 2024Article
90 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gallbladder cancer (GBC) is an uncommon disease in the majority of the world despite being the most common and aggressive malignancy of the biliary tree. Early diagnosis is essential for improved prognosis; however, indolent and nonspecific clinical presentations with a paucity of pathognomonic/predictive radiological features often preclude accurate identification of GBC at an early stage. As such, GBC remains a highly lethal disease, with only 10% of all patients presenting at a stage amenable to surgical resection. Among this select population, continued improvements in survival during the 21st century are attributable to aggressive radical surgery with improved surgical techniques. This paper reviews the current available literature of the 21st century on PubMed and Medline to provide a detailed summary of the epidemiology and risk factors, pathogenesis, clinical presentation, radiology, pathology, management, and prognosis of GBC.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.