ReviewInternational journal of endocrinology2015
Influence of CAG Repeat Polymorphism on the Targets of Testosterone Action.
Review in International journal of endocrinology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 83 citations in OpenAlex.
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- Review
- Androgen receptor gene polymorphism and biological age markers in men.Scientific reports · 2025Article
- The Influence of Trinucleotide Repeats in the Androgen Receptor Gene on Androgen-related Traits and Diseases.The Journal of clinical endocrinology and metabolism · 2024Article
- Erectile function and androgen and estrogen beta receptor gene polymorphisms in acromegalic men.Journal of endocrinological investigation · 2024Article
- Preimplantation Genetic Diagnosis of Androgen Resistance Syndrome Caused by Mutation on theThe application of clinical genetics · 2024Article
- Adult Male Hypogonadism: A Laboratory Medicine Perspective on Its Diagnosis and Management.Diagnostics (Basel, Switzerland) · 2023Review
- Standardising the biochemical confirmation of adult male hypogonadism; a joint position statement by the Society for Endocrinology and Association of Clinical Biochemistry and Laboratory Medicine.Annals of clinical biochemistry · 2023Article
- Splicing Modulators Are Involved in Human Polyglutamine Diversification via Protein Complexes Shuttling between Nucleus and Cytoplasm.International journal of molecular sciences · 2023Article
- Article
- Association between androgen receptor gene alteration and osteoporosis in Chinese Han elderly men.PeerJ · 2023Article
- [Androgens and Parkinson's disease: the role in humans and in experiment].Problemy endokrinologii · 2022Review
- Genetic Implications of Male-Reproductive-Health-Associated Comorbidities.Turkish journal of urology · 2022Article
- Homocysteine levels correlate with velocimetric parameters in patients with erectile dysfunction undergoing penile duplex ultrasound.Andrology · 2022Article
- Genetics and erectile dysfunction: leveraging early foundations for new discoveries.International journal of impotence research · 2022Review
- Androgen receptor polymorphism, testosterone levels, and prognosis in patients with acute myocardial infarction.European heart journal open · 2021Article
- Androgen receptor-reduced sensitivity is associated with increased mortality and poorer glycaemia in men with type 2 diabetes mellitus: a prospective cohort study.Cardiovascular endocrinology & metabolism · 2021Article
- Androgens and Parkinson's Disease: A Review of Human Studies and Animal Models.Androgens: clinical research and therapeutics · 2021Review
- The Double Edge Sword of Testosterone's Role in the COVID-19 Pandemic.Frontiers in endocrinology · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the last decade, ample evidence has demonstrated the growing importance of androgen receptor (AR) CAG repeat polymorphism in andrology. This genetic parameter is able to condition the peripheral effects of testosterone and therefore to influence male sexual function and fertility, cardiovascular risk, body composition, bone metabolism, the risk of prostate and testicular cancer, the psychiatric status, and the onset of neurodegenerative disorders. In this review, we extensively discuss the literature data and identify a role for AR CAG repeat polymorphism in conditioning the systemic testosterone effects. In particular, our main purpose was to provide an updated text able to shed light on the many and often contradictory findings reporting an influence of CAG repeat polymorphism on the targets of testosterone action.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.