Evidence map›Paper›PMID 26420914›Full record

ArticleDisease markers2015

Serum and Vitreous Concentrations of Omentin-1 in Diabetic Retinopathy.

Wencui Wan, Qiuming Li, Fengyan Zhang, Guangying Zheng, Yong Lv, Guangming Wan, Xuemin Jin

Open access · hybridAbstract read
In one paragraph

Article in Disease markers, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Omentin-A Novel Adipokine in Respiratory Diseases.International journal of molecular sciences · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Wencui WanDepartment of Ophthalmology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Qiuming LiDepartment of Ophthalmology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Fengyan ZhangDepartment of Ophthalmology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Guangying ZhengDepartment of Ophthalmology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Yong LvDepartment of Ophthalmology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Guangming WanDepartment of Ophthalmology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Xuemin JinDepartment of Ophthalmology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
First Affiliated Hospital of Zhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveOmentin, a new discovered adipokine, is implicated to inhibit inflammation. Inflammation is one important mechanism of diabetic retinopathy (DR). The purpose of this work was to evaluate serum and vitreous concentrations of omentin-1 in patients with diabetic retinopathy (DR).

methodsThis study enrolled 204 diabetic patients (60 without DR, 49 with NPDR, and 95 with PDR) and 65 control subjects.

resultsSerum and vitreous omentin-1 levels in PDR patients were markedly decreased compared with those in the other three groups. NPDR patients showed reduced vitreous omentin-1 compared with patients without DR. In addition, control subjects had significantly higher levels of serum and vitreous omentin-1 compared with diabetic patients without DR, NPDR patients, and PDR patients. In addition, serum/vitreous omentin-1 ratio was positively correlated with the development and severity of DR.

conclusionSerum and vitreous omentin-1 levels, as well as serum/vitreous omentin-1 ratio, are correlated with the presence and severity of DR.

Indexed as

AgedCase-Control StudiesCytokinesDiabetic RetinopathyFemaleGPI-Linked ProteinsHumansLectinsMaleMiddle AgedVitreous BodyCytokinesGPI-Linked ProteinsITLN1 protein, humanLectins

Identifiers

PMID26420914
PMCPMC4573431
OpenAlexW1680706728

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.