ArticleNucleic acids research2015
The players may change but the game remains: network analyses of ruminal microbiomes suggest taxonomic differences mask functional similarity.
Article in Nucleic acids research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.
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Who cites it
73 citing papers in PubMed.
- Impact of Opuntia spp. by-product silage on sheep metabolic profile, rumen fermentation and microbial communities.BMC veterinary research · 2026Article
- Rumen Microbiome Development in Lambs Following Maternal and Early-Life Prebiotic Mannan-Rich Fraction (MRF) Supplementation.Animals : an open access journal from MDPI · 2026Article
- Two kinds of evolutionary individuals: the concept of common interest as an evolutionary foundation of dualism on biological individuality.History and philosophy of the life sciences · 2026Article
- Core rumen microbes are functional generalists that sustain host metabolism and gut ecosystem function.Nature ecology & evolution · 2026Article
- Effects of lubabegron fumarate on ruminal fermentation and microbial community in a rumen simulation system.Frontiers in microbiology · 2026Article
- Review: Shifts of rumen microbiota by feeding non-fibrous carbohydrates to improve cattle performance.Frontiers in microbiology · 2026Review
- Gut Morphological Structure-Microbial Characteristics inAnimals : an open access journal from MDPI · 2025Article
- Comparative analysis of ruminal and fecal microbiomes in Holstein, Jersey, and Jeju Black cattle using multiple taxonomic classifiers.Animal biotechnology · 2025Article
- Anaerobic fungi: effective warriors in lignocellulosic biomass degradation and fermentation.FEMS microbiology ecology · 2025Review
- Retrospective analysis of antimicrobial resistance associated with bovine respiratory disease.Applied and environmental microbiology · 2025Article
- Network analyses unraveled the complex interactions in the rumen microbiota associated with methane emission in dairy cattle.Animal microbiome · 2025Article
- Gut Microbiota of Ruminants and Monogastric Livestock: An Overview.Animals : an open access journal from MDPI · 2025Review
- Functional team selection as a framework for local adaptation in plants and their belowground microbiomes.The ISME journal · 2025Review
- The Effects of Animal, Collection Time, and Interval on the Microbiota Structure, Metabolism, and Degradative Potential of Rumen Fluid Inoculum Collected by Esophageal Probe from Hay-Fed Cows.Animals : an open access journal from MDPI · 2024Article
- Prickly Ash Seeds Improve the Ruminal Epithelial Development and Growth Performance of Hu Sheep by Modulating the Rumen Microbiota and Metabolome.Microorganisms · 2024Article
- Whole-Genome Metagenomic Analysis of Functional Profiles in the Fecal Microbiome of Farmed Sows with Different Reproductive Performances.Microorganisms · 2024Article
- Rumen and hindgut microbiome regulate average daily gain of preweaning Holstein heifer calves in different ways.Microbiome · 2024Article
- Single-cell transcriptomics across 2,534 microbial species reveals functional heterogeneity in the rumen microbiome.Nature microbiology · 2024Article
- Effects of diets for three growing stages by rumen inocula donors onJournal of animal science and technology · 2024Article
- - Invited Review - Understanding the functionality of the rumen microbiota: searching for better opportunities for rumen microbial manipulation.Animal bioscience · 2024Article
13 more citing papers are in PubMed but not listed here.
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
By mapping translated metagenomic reads to a microbial metabolic network, we show that ruminal ecosystems that are rather dissimilar in their taxonomy can be considerably more similar at the metabolic network level. Using a new network bi-partition approach for linking the microbial network to a bovine metabolic network, we observe that these ruminal metabolic networks exhibit properties consistent with distinct metabolic communities producing similar outputs from common inputs. For instance, the closer in network space that a microbial reaction is to a reaction found in the host, the lower will be the variability of its enzyme copy number across hosts. Similarly, these microbial enzymes that are nearby to host nodes are also higher in copy number than are more distant enzymes. Collectively, these results demonstrate a widely expected pattern that, to our knowledge, has not been explicitly demonstrated in microbial communities: namely that there can exist different community metabolic networks that have the same metabolic inputs and outputs but differ in their internal structure.
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