ReviewMolecular diversity2016
Molecular diversity of spirooxindoles. Synthesis and biological activity.
Review in Molecular diversity, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
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Who cites it
39 citing papers in PubMed.
- Evaluation of novel 1,4-dihydropyridine spirooxindole as antitumor, anti-inflammatory, and antioxidant agents.RSC advances · 2026Article
- Organocatalytic Enantio- and Diastereoselective Synthesis of Dispirooxindole Derivatives with Adjacent Spirocyclic Centers via [4 + 2] Cycloadditions.The Journal of organic chemistry · 2026Article
- Synthetic advances, pharmacological prospects, and molecular insights of spirooxindoles: a comprehensive review.Journal of molecular modeling · 2026Review
- Synthesis of novel spiro[chromeno[2,3-d][1,3,4]thiadiazolo[3,2-a] pyrimidines via an isatin-based three-component reaction.Scientific reports · 2025Article
- Enantioselective Synthesis of Spirocyclic Isoxazolones Using a Conia-Ene Type Reaction.The Journal of organic chemistry · 2025Article
- Quantitative structure-activity relationship and ADME prediction studies on series of spirooxindoles derivatives forHeliyon · 2024Article
- Article
- DBU-catalyzed diastereoselective 1,3-dipolar [3+2] cycloaddition of trifluoroethyl amine-derived isatin ketimines with chalcones: synthesis of 5'-CFRSC advances · 2024Article
- Small Molecules with Spiro-Conjugated Cycles: Advances in Synthesis and Applications.International journal of molecular sciences · 2023Article
- Article
- Stereoselective synthesis of CFRSC advances · 2023Review
- Anticonvulsant activity, molecular modeling and synthesis of spirooxindole-4H-pyran derivatives using a novel reusable organocatalyst.Molecular diversity · 2022Article
- Synthesis, Structure and Stereochemistry of Dispirocompounds Based on Imidazothiazolotriazine and Pyrrolidineoxindole.International journal of molecular sciences · 2022Article
- Lewis acid-catalyzed [4 + 2] cycloaddition of donor-acceptor cyclobutanes with iminooxindoles: access to spiro[piperidine-3,2'-oxindoles].RSC advances · 2022Article
- Ultrasound-assisted transition-metal-free catalysis: a sustainable route towards the synthesis of bioactive heterocycles.RSC advances · 2022Review
- Tri(Beilstein journal of organic chemistry · 2022Article
- A facile approach to spiro[dihydrofuran-2,3'-oxindoles] via formal [4 + 1] annulation reaction of fused 1Beilstein journal of organic chemistry · 2022Article
- Synthesis and Biological Evaluation of S-, O- and Se-Containing Dispirooxindoles.Molecules (Basel, Switzerland) · 2021Article
- Preparation of GO/SiORSC advances · 2021Article
- Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Spirooxindoles are important synthetic targets possessing extended biological activity and drug discovery applications. This review focuses on the various strategies for the enantioselective synthesis of spirocyclic oxindoles relying on reports over the past decade and from earlier work. The spirooxindoles in this review are separated into three structural classes, and then further categorized into the method type from which the spirocycle is generated.
Indexed as
Identifiers
26419598What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.