DLL4 loss-of-function heterozygous mutations cause Adams-Oliver syndrome.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

5 citing papers in PubMed, 17 citations in OpenAlex.

1. Targeted sequencing of NOTCH signaling pathway genes and association analysis of variants correlated with mandibular prognathism.Head & face medicine · 2021
   Article
2. Functional genomics and gene-environment interaction highlight the complexity of congenital heart disease caused by Notch pathway variants.Human molecular genetics · 2020
   Article
3. Congenital diseases caused by defectiveNagoya journal of medical science · 2018
   Review
4. O-GlcNAc on NOTCH1 EGF repeats regulates ligand-induced Notch signaling and vascular development in mammals.eLife · 2017
   Article
5. Mapping Sites of O-Glycosylation and Fringe Elongation on Drosophila Notch.The Journal of biological chemistry · 2016
   Article

Corrections and comments

• Comment on
  Heterozygous Loss-of-Function Mutations in DLL4 Cause Adams-Oliver Syndrome.2015

Authors and funding

1 author at 1 institution in 1 country.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as