ArticleParasites & vectors2015
Studies of trypanosomiasis in the Luangwa valley, north-eastern Zambia.
Article in Parasites & vectors, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 16 papers.
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16 citing papers in PubMed, 39 citations in OpenAlex.
- Developing a national atlas to support the progressive control of tsetse-transmitted animal trypanosomosis in Zambia.Parasites & vectors · 2025Article
- Domestic dogs as reservoirs for African trypanosomiasis in Mambwe district, eastern Zambia.Scientific reports · 2024Article
- Prevalence and Association of Trypanosomes andTropical medicine and infectious disease · 2023Article
- The detection of African trypanosomes in goats reared in tsetse infested villages of Eastern Zambia.Tropical animal health and production · 2022Article
- Healthcare Management of Human African Trypanosomiasis Cases in the Eastern, Muchinga and Lusaka Provinces of Zambia.Tropical medicine and infectious disease · 2022Article
- Ethical dimensions of zoonotic disease research: Perspectives of traditional livestock keepers in Zambia.Wellcome open research · 2022Article
- Evidence ofMicroorganisms · 2021Article
- Genetic Diversity of African Trypanosomes in Tsetse Flies and Cattle From the Kafue Ecosystem.Frontiers in veterinary science · 2021Article
- Parasitological and molecular detection ofParasitology · 2020Article
- Diversity of trypanosomes in wildlife of the Kafue ecosystem, Zambia.International journal for parasitology. Parasites and wildlife · 2020Article
- Insights into the Control and Management of Human and Bovine African Trypanosomiasis in Zambia between 2009 and 2019-A Review.Tropical medicine and infectious disease · 2020Review
- Genetic diversity and population structure of Glossina morsitans morsitans in the active foci of human African trypanosomiasis in Zambia and Malawi.PLoS neglected tropical diseases · 2019Article
- Article
- New insights from Gorongosa National Park and Niassa National Reserve of Mozambique increasing the genetic diversity of Trypanosoma vivax and Trypanosoma vivax-like in tsetse flies, wild ungulates and livestock from East Africa.Parasites & vectors · 2017Article
- Ungulate malaria parasites.Scientific reports · 2016Article
- Erratum to: Studies of trypanosomiasis in the Luangwa valley, north-eastern Zambia.Parasites & vectors · 2015Article
Corrections and comments
- Erratum issuedErratum to: Studies of trypanosomiasis in the Luangwa valley, north-eastern Zambia.2015 · Goto, Yasuhuki [corrected to Goto, Yasuyuki]
Authors and funding
11 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe present study, conducted in Zambia's Luangwa valley where both animal African trypanosomiasis (AAT) and human African trypanosomiasis (HAT) are endemic, combined the use of microscopy and molecular techniques to determine the presence of trypanosome species in cattle, goats and tsetse flies.
methodsThis study was conducted between 2008 and 2010 in Petauke, Chama and Isoka districts, north-eastern Zambia. A total of 243 cattle, 36 goats and 546 tsetse flies, were examined for presence of trypanosome species using microscopy, PCR and loop-mediated isothermal amplification (LAMP).
resultsThere was poor agreement among the test methods used for detection of trypanosomes species in animal blood and tsetse flies. Trypanosomes were observed in 6.1 % (95 % CI: 3.3-8.9 %) of the animals sampled by microscopy, 7.5 % (95 % CI: 4.4-10.6 %) by PCR and 18.6 % (95 % CI: 13.6-23.6 %) by PFR-LAMP. PFR-LAMP was more sensitive for detecting Trypanozoon than KIN-PCR. The highest occurrence of AAT was recorded in cattle from Petauke (58.7 %, 95 % CI: 44.7-72.7 %) while the lowest was from Isoka (5.4 %, 95 % CI: 0.8-10.0 %). Infection of both cattle and goats with Trypanosoma congolense and T. vivax was associated with clinical AAT.
conclusionWhen selecting molecular techniques for AAT surveillance in endemic regions, the KIN-PCR and species-specific PCR may be recommended for screening animal or tsetse fly samples for T. congolense and T. vivax, respectively. On the other hand, species-specific PCR and/or LAMP might be of greater value in the screening of animal and human body fluids as well as tsetse fly samples for Trypanozoon.
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