ArticleNature communications2015
Limited dissemination of the wastewater treatment plant core resistome.
Article in Nature communications, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.
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Who cites it
61 citing papers in PubMed.
- Long-Term Application of Fermented Fertilizer Attenuates the Accumulation of Antibiotic Resistance Genes in Aquaculture Sediment.Microorganisms · 2026Article
- Global diversity and distribution of antibiotic resistance genes in human wastewater treatment systems.Nature communications · 2025Article
- Global analysis of the metaplasmidome: ecological drivers and spread of antibiotic resistance genes across ecosystems.Microbiome · 2025Article
- The Impact of Wastewater on Antimicrobial Resistance: A Scoping Review of Transmission Pathways and Contributing Factors.Antibiotics (Basel, Switzerland) · 2025Review
- Selection and horizontal gene transfer underlie microdiversity-level heterogeneity in resistance gene fate during wastewater treatment.Nature communications · 2024Article
- Metagenomic approach revealed the mobility and co-occurrence of antibiotic resistomes between non-intensive aquaculture environment and human.Microbiome · 2024Article
- Highly accurate classification and discovery of microbial protein-coding gene functions using FunGeneTyper: an extensible deep learning framework.Briefings in bioinformatics · 2024Article
- Axenic green microalgae for the treatment of textile effluent and the production of biofuel: a promising sustainable approach.World journal of microbiology & biotechnology · 2024Article
- Global diversity and biogeography of DNA viral communities in activated sludge systems.Microbiome · 2023Article
- Colonization-persistence trade-offs in natural bacterial communities.Proceedings. Biological sciences · 2023Article
- ResFinderFG v2.0: a database of antibiotic resistance genes obtained by functional metagenomics.Nucleic acids research · 2023Article
- Article
- Antibiotic resistance gene sequencing is necessary to reveal the complex dynamics of immigration from sewers to activated sludge.Frontiers in microbiology · 2023Article
- Demonstrating a Comprehensive Wastewater-Based Surveillance Approach That Differentiates Globally Sourced Resistomes.Environmental science & technology · 2022Article
- Article
- Article
- Article
- Recovery of High Quality Metagenome-Assembled Genomes From Full-Scale Activated Sludge Microbial Communities in a Tropical Climate Using Longitudinal Metagenome Sampling.Frontiers in microbiology · 2022Article
- A Novel Efficient L-Lysine Exporter Identified by Functional Metagenomics.Frontiers in microbiology · 2022Article
- Evolutionary Pathways and Trajectories in Antibiotic Resistance.Clinical microbiology reviews · 2021Article
1 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Horizontal gene transfer is a major contributor to the evolution of bacterial genomes and can facilitate the dissemination of antibiotic resistance genes between environmental reservoirs and potential pathogens. Wastewater treatment plants (WWTPs) are believed to play a central role in the dissemination of antibiotic resistance genes. However, the contribution of the dominant members of the WWTP resistome to resistance in human pathogens remains poorly understood. Here we use a combination of metagenomic functional selections and comprehensive metagenomic sequencing to uncover the dominant genes of the WWTP resistome. We find that this core resistome is unique to the WWTP environment, with <10% of the resistance genes found outside the WWTP environment. Our data highlight that, despite an abundance of functional resistance genes within WWTPs, only few genes are found in other environments, suggesting that the overall dissemination of the WWTP resistome is comparable to that of the soil resistome.
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