Evidence map›Paper›PMID 26419246›Full record

Observational studyGeneral thoracic and cardiovascular surgery2015

The relationship between perioperative administration of inhaled corticosteroid and postoperative respiratory complications after pulmonary resection for non-small-cell lung cancer in patients with chronic obstructive pulmonary disease.

Keiji Yamanashi, Satoshi Marumo, Tsuyoshi Shoji, Takamasa Fukui, Ryota Sumitomo, Yosuke Otake, Minoru Sakuramoto, Motonari Fukui, Cheng-Long Huang

Abstract readObservational Study

PubMed Publisher

In one paragraph

Observational study in General thoracic and cardiovascular surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it

0cells of the map it votes in

8citing papers in PubMed

1.4field-weighted citation impact, top 17% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

Construction of an automated machine learning-based predictive model for postoperative pulmonary complications risk in non-small cell lung cancer patients undergoing thoracoscopic surgery.PloS one · 2025
Article
Incidence of postoperative pneumonia in various surgical subspecialties: a retrospective study.Annals of medicine and surgery (2012) · 2024
Article
Chronic Obstructive Pulmonary Disease and Lung Cancer: Underlying Pathophysiology and New Therapeutic Modalities.Drugs · 2018
Review
Preoperative management using inhalation therapy for pulmonary complications in lung cancer patients with chronic obstructive pulmonary disease.General thoracic and cardiovascular surgery · 2017
Article
Long acting βJournal of cardiothoracic surgery · 2017
Article
Lung cancer and chronic obstructive pulmonary disease: From a clinical perspective.Oncotarget · 2017
Review
Chronic obstructive pulmonary disease in patients with lung cancer: prevalence, impact and management challenges.Lung Cancer (Auckland, N.Z.) · 2017
Review
Impact of chemotherapy in the prognosis of non-small-cell lung cancer patients with severe to very severe COPD.International journal of chronic obstructive pulmonary disease
Observational

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Keiji YamanashiRespiratory Disease Center, Tazuke Kofukai Foundation, Medical Research Institute, Kitano Hospital, 2-4-20 Ohgimachi, Kita-ku, Osaka, 530-8480, Japan.

Satoshi MarumoRespiratory Disease Center, Tazuke Kofukai Foundation, Medical Research Institute, Kitano Hospital, 2-4-20 Ohgimachi, Kita-ku, Osaka, 530-8480, Japan. marumo@kuhp.kyoto-u.ac.jp.

Tsuyoshi ShojiDepartment of Thoracic Surgery, Japanese Red Cross Otsu Hospital, Shiga, Japan.

Takamasa FukuiRespiratory Disease Center, Tazuke Kofukai Foundation, Medical Research Institute, Kitano Hospital, 2-4-20 Ohgimachi, Kita-ku, Osaka, 530-8480, Japan.

Ryota SumitomoRespiratory Disease Center, Tazuke Kofukai Foundation, Medical Research Institute, Kitano Hospital, 2-4-20 Ohgimachi, Kita-ku, Osaka, 530-8480, Japan.

Yosuke OtakeRespiratory Disease Center, Tazuke Kofukai Foundation, Medical Research Institute, Kitano Hospital, 2-4-20 Ohgimachi, Kita-ku, Osaka, 530-8480, Japan.

Minoru SakuramotoRespiratory Disease Center, Tazuke Kofukai Foundation, Medical Research Institute, Kitano Hospital, 2-4-20 Ohgimachi, Kita-ku, Osaka, 530-8480, Japan.

Motonari FukuiRespiratory Disease Center, Tazuke Kofukai Foundation, Medical Research Institute, Kitano Hospital, 2-4-20 Ohgimachi, Kita-ku, Osaka, 530-8480, Japan.

Cheng-Long HuangRespiratory Disease Center, Tazuke Kofukai Foundation, Medical Research Institute, Kitano Hospital, 2-4-20 Ohgimachi, Kita-ku, Osaka, 530-8480, Japan.

Kitano Hospital · JPOtsu Red Cross Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesInhaled corticosteroid (ICS) treatment has been shown to increase the risk of respiratory complications in patients with stable chronic obstructive pulmonary disease (COPD). However, the effects of perioperative ICS treatment on postoperative respiratory complications after lung cancer surgery have not been elucidated. The aim of this study was to investigate whether perioperative ICS treatment would increase the risk of postoperative respiratory complications after lung cancer surgery in patients with COPD.

methodsWe retrospectively analyzed 174 consecutive COPD patients with non-small-cell lung cancer (NSCLC) who underwent lobectomy or segmentectomy between January 2007 and December 2014. Subjects were grouped based on whether or not they were administered perioperative ICS treatment. Postoperative cardiopulmonary complications were compared between the groups.

resultsThere were no statistically significant differences in the incidence of postoperative respiratory complications (P = 0.573) between the perioperative ICS treatment group (n = 16) and the control group (n = 158). Perioperative ICS treatment was not significantly associated with postoperative respiratory complications in the univariate or multivariate analysis (odds ratio [OR] = 0.553, 95% confidence interval [CI] = 0.069-4.452, P = 0.578; OR = 0.635, 95% CI = 0.065-6.158, P = 0.695, respectively). Kaplan-Meier analysis showed that there were no statistically significant differences in the postoperative respiratory complications-free durations between the groups (P = 0.566), even after propensity score matching (P = 0.551).

conclusionThere was no relationship between perioperative ICS administration and the incidences of postoperative respiratory complications after surgical resection for NSCLC in COPD patients.

Indexed as

PneumonectomyAdministration, InhalationAdrenal Cortex HormonesAgedAged, 80 and overCarcinoma, Non-Small-Cell LungEpidemiologic MethodsFemaleHumansLung DiseasesLung NeoplasmsMalePerioperative CarePneumoniaPostoperative ComplicationsPulmonary AtelectasisAdrenal Cortex HormonesInhaled corticosteroidLung cancer surgeryPostoperative respiratory complications

Identifiers

PMID26419246

DOI10.1007/s11748-015-0593-0

OpenAlexW2184862697

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.