Evidence map›Paper›PMID 26418681›Full record

ArticlePloS one2015

Multi-Etiological Nature of Tuberculosis-Like Lesions in Condemned Pigs at the Slaughterhouse.

Fernando Cardoso-Toset, Jaime Gómez-Laguna, Shyrley P Amarilla, Ana I Vela, Librado Carrasco, Jose F Fernández-Garayzábal, Rafael J Astorga, Inmaculada Luque

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Fernando Cardoso-TosetDepartment of Animal Health, Faculty of Veterinary Medicine, 'International Excellence Agrifood Campus, CeiA3', Córdoba, Spain; Department of R&D, CICAP - Food Research Centre, Pozoblanco, Córdoba, Spain.
Jaime Gómez-LagunaDepartment of R&D, CICAP - Food Research Centre, Pozoblanco, Córdoba, Spain.
Shyrley P AmarillaDepartment of Anatomy and Comparative Pathology, Faculty of Veterinary Medicine, 'International Excellence Agrifood Campus, CeiA3', Córdoba, Spain.
Ana I VelaDepartment of Animal Health, Faculty of Veterinary Medicine, Complutense University, Madrid, Spain; VISAVET Health Surveillance Centre, Faculty of Veterinary Medicine, Complutense University, Madrid, Spain.
Librado CarrascoDepartment of Anatomy and Comparative Pathology, Faculty of Veterinary Medicine, 'International Excellence Agrifood Campus, CeiA3', Córdoba, Spain.
Jose F Fernández-GarayzábalDepartment of Animal Health, Faculty of Veterinary Medicine, Complutense University, Madrid, Spain; VISAVET Health Surveillance Centre, Faculty of Veterinary Medicine, Complutense University, Madrid, Spain.
Rafael J AstorgaDepartment of Animal Health, Faculty of Veterinary Medicine, 'International Excellence Agrifood Campus, CeiA3', Córdoba, Spain.
Inmaculada LuqueDepartment of Animal Health, Faculty of Veterinary Medicine, 'International Excellence Agrifood Campus, CeiA3', Córdoba, Spain.
Universidad Complutense de Madrid · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tuberculosis-like lesions (TBL) in pigs have been associated with microorganisms other than mycobacteria. In this work a histopathological and microbiological evaluation of TBL in pigs is shown. A total of 352 samples belonging to 171 pigs totally condemned at slaughterhouse due to generalized TBL were sampled and selected for analysis. Pyogranulomatous (56.2%) and granulomatous lesions (20.2%) were observed in all analysed organs. Most of the granulomas observed in both lymph nodes and lungs belonged to more advanced stages of development (stages III and IV) whereas in the liver and the spleen most of lesions belonged to intermediate stages (stages II and III). Different microorganisms were simultaneously detected from TBL in the 42.7% of the animals. Mycobacterium tuberculosis complex (MTC) (38%), coryneform bacteria (40.3%) and streptococci (28.1%) were the main groups of microorganisms detected after bacteriological analysis, with Trueperella pyogenes and Streptococcus suis as the most frequently isolated species. Mycobacteria belonging to MTC were the most frequently detected pathogens in granulomatous and pyogranulomatous lesions in submandibular lymph nodes (32.7%) and coryneform bacteria were the microorganisms more frequently isolated from lungs (25.9%) and spleen samples (37.2%). These results may provide new insights into the pathogenesis and diagnosis of this pathology. The importance of coryneform bacteria and streptococci in such processes must be evaluated in future studies.

Indexed as

AbattoirsAnimalsCorynebacteriumGranulomaLymph NodesMycobacterium tuberculosisRNA, Ribosomal, 16SStaphylococcusStreptococcus suisSwineSwine DiseasesTuberculosisRNA, Ribosomal, 16S

Identifiers

PMID26418681
PMCPMC4587938
OpenAlexW2176666185

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.