Evidence map›Paper›PMID 26418558›Full record

ArticlePlant signaling & behavior2015

Mitigation of copper toxicity by DNA oligomers in green paramecia.

Hiroshi Takaichi, Diego Comparini, Junichiro Iwase, François Bouteau, Stefano Mancuso, Tomonori Kawano

Open access · bronzeAbstract read
In one paragraph

Article in Plant signaling & behavior, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 5 countries.

Hiroshi Takaichia Laboratory of Chemical Biology and Bioengineering; Faculty and Graduate School of Environmental Engineering; The University of Kitakyushu ; Kitakyushu , Japan.
Diego Comparinia Laboratory of Chemical Biology and Bioengineering; Faculty and Graduate School of Environmental Engineering; The University of Kitakyushu ; Kitakyushu , Japan.
Junichiro Iwaseb University of Florence; LINV Kitakyushu Research Center (LINV@Kitakyushu) ; Kitakyushu , Japan.
François Bouteaub University of Florence; LINV Kitakyushu Research Center (LINV@Kitakyushu) ; Kitakyushu , Japan.
Stefano Mancusob University of Florence; LINV Kitakyushu Research Center (LINV@Kitakyushu) ; Kitakyushu , Japan.
Tomonori Kawanoa Laboratory of Chemical Biology and Bioengineering; Faculty and Graduate School of Environmental Engineering; The University of Kitakyushu ; Kitakyushu , Japan.
Sorbonne Paris Cité · FRBioengineering (Switzerland) · CHThe University of Kitakyushu · JPUniversité Paris Cité · FRUniversity of Florence · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Impact of transition metals which catalyze the generation of reactive oxygen species (ROS), on activation of cell death signaling in plant cells have been documented to date. Similarly in green paramecia (Paramecium bursaria), an aquatic protozoan species harboring symbiotic green algae in the cytoplasm, toxicities of various metallic ions have been documented. We have recently examined the effects of double-stranded GC-rich DNA fragments with copper-binding nature and ROS removal catalytic activity as novel plant cell-protecting agents, using the suspension-cultured tobacco cells. Here, we show that above DNA oligomers protect the cells of green paramecia from copper-induced cell death, suggesting that the phenomenon firstly observed in tobacco cells is not limited only within higher plants but it could be universally observable in wider range of organisms.

Indexed as

Base CompositionBase SequenceCell DeathCopperCytoprotectionDNAMolecular Sequence DataParameciumCopperDNAcell deathDNA oligomersgreen algaemetal toxicityROS

Identifiers

PMID26418558
PMCPMC4883909
OpenAlexW2280404957

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.