Evidence map›Paper›PMID 26418054›Full record

ArticleClinical pharmacology and therapeutics2016

Providing Access to Genomic Variant Knowledge in a Healthcare Setting: A Vision for the ClinGen Electronic Health Records Workgroup.

C L Overby, B Heale, S Aronson, J M Cherry, S Dwight, A Milosavljevic, T Nelson, A Niehaus, M A Weaver, E M Ramos and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical pharmacology and therapeutics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. An ancillary genomics system to support the return of pharmacogenomic results.Journal of the American Medical Informatics Association : JAMIA · 2019
    Article
  2. Review
  3. Article
  4. Enhancing Electronic Health Record Data with Geospatial Information.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2017
    Article
  5. Article
  6. ENCODE data at the ENCODE portal.Nucleic acids research · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

C L OverbyProgram for Personalized and Genomic Medicine & Center for Health-related Informatics and Bioimaging, University of Maryland School of Medicine, Baltimore, Maryland, USA.
B HealeUniversity of Utah, Salt Lake City, Utah, USA.
S AronsonPartners HealthCare Personalized Medicine, Cambridge, Massachusetts, USA.
J M CherryStanford University, School of Medicine, Stanford, California, USA.
S DwightStanford University, School of Medicine, Stanford, California, USA.
A MilosavljevicBaylor College of Medicine, Houston, Texas, USA.
T NelsonGenomic Medicine Institute, Geisinger Health System, Danville, Pennsylvania, USA.
A NiehausNational Human Genome Research Institute, National Institutes of Health, Rockville, Maryland, USA.
M A WeaverAmerican College of Medical Genetics and Genomics, Bethesda, Maryland, USA.
E M RamosNational Human Genome Research Institute, National Institutes of Health, Rockville, Maryland, USA.
M S WilliamsGenomic Medicine Institute, Geisinger Health System, Danville, Pennsylvania, USA.

Funding

Resource ProjectU41HG006834 · NHGRI · BRIGHAM AND WOMEN'S HOSPITAL · PI REHM, HEIDI L · 2013 to 2020
$26.9M
UNIVERSITY OF UTAH MEDICAL INFORMATICS TRAININGT15LM007124 · NLM · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Karen Louise Eilbeck · 1997 to 2026
$22.0M
The Clinical Genome Resource - Expert Curation and EHR IntegrationU41HG009650 · NHGRI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BERG, JONATHAN S · 2017 to 2020
$13.3M
Clinically Relevant Genome Variation DatabaseU01HG007436 · NHGRI · STANFORD UNIVERSITY · PI BUSTAMANTE, CARLOS DANIEL, PLON, SHARON E. · 2013 to 2016
$10.5M
A Knowledge Base for Clinically Relevant Genes and VariantsU01HG007437 · NHGRI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BERG, JONATHAN S, EVANS, JAMES PHILIP · 2013 to 2016
$9.0M
CCR NIH HHS HHSN261200800001CNCI NIH HHS HHSN261200800001ENHGRI NIH HHS 1U01HG007436-01NHGRI NIH HHS 1U01HG007437-01NHGRI NIH HHS 1U41HG006834-01A1NHGRI NIH HHS U01 HG007436NHGRI NIH HHS U01 HG007437NHGRI NIH HHS U41 HG006834NHGRI NIH HHS U41 HG009650NLM NIH HHS T15LM007124
6 · The paper itself

Abstract

The Clinical Genome Resource (ClinGen) is a National Institutes of Health (NIH)-funded collaborative program that brings together a variety of projects designed to provide high-quality, curated information on clinically relevant genes and variants. ClinGen's EHR (Electronic Health Record) Workgroup aims to ensure that ClinGen is accessible to providers and patients through EHR and related systems. This article describes the current scope of these efforts and progress to date. The ClinGen public portal can be accessed at www.clinicalgenome.org.

Indexed as

Databases, GeneticElectronic Health RecordsGenetic VariationHumansPharmacogeneticsPrecision Medicine

Identifiers

PMID26418054
PMCPMC4724305

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.