Evidence map›Paper›PMID 26417965›Full record

Observational studyCOPD2016

Emergency Hospital Care for Exacerbation of COPD: Is Inhaled Maintenance Therapy Modified?

Xavier Pomares, Concepción Montón, Marisa Baré, Marina Pont, Cristina Estirado, Joaquim Gea, José Maria Quintana, Silvia Vidal, Ana Santiago, IRYSS-COPD Appropriateness study group

Registry-linked trialAbstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in COPD, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02434536 (Assessment of the Appropriateness Admission From Emergency Departments in the Exacerbation of COPD. Validity of Explicit Criteria and Study of the Variability Between Different Centers of NHS. Multicenter Study IRYSS-Appropriateness-COPD.), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02434536 completednot on this map

Assessment of the Appropriateness Admission From Emergency Departments in the Exacerbation of COPD. Validity of Explicit Criteria and Study of the Variability Between Different Centers of NHS. Multicenter Study IRYSS-Appropriateness-COPD.

Typeobservational_patient_registrySponsorHospital Galdakao-UsansoloRan2006 to 2010Enrolled2,487ConditionsCOPD
3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 6 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 1 country.

Xavier Pomaresa Department of Respiratory Medicine , Parc Taulí Sabadell - University Hospital , Sabadell , Spain.
Concepción Montóna Department of Respiratory Medicine , Parc Taulí Sabadell - University Hospital , Sabadell , Spain.
Marisa Baréc Clinical Epidemiology , Parc Taulí Sabadell - University Hospital , Sabadell , Spain.
Marina Pontc Clinical Epidemiology , Parc Taulí Sabadell - University Hospital , Sabadell , Spain.
Cristina Estiradoe Pulmonology Department, Hospital del Mar - IMIM. CEXS , Universitat Pompeu Fabra , Barcelona , Catalonia , Spain.
Joaquim Geae Pulmonology Department, Hospital del Mar - IMIM. CEXS , Universitat Pompeu Fabra , Barcelona , Catalonia , Spain.
José Maria Quintanaf Research Unit, Galdakao Hospital , Bilbao , Spain.
Silvia Vidalg Research Unit, Hospital Costa del Sol , Marbella , Spain.
Ana Santiagoh Pulmonology Department. Hospital , La Paz . Madrid , Spain.
IRYSS-COPD Appropriateness study group
Deleted InstitutionPompeu Fabra University · ESHospital Costa del Sol · ESHospital de Galdakao · ESHospital Universitario La Paz · ESInstituto de Salud Carlos III · ESUniversitat Autònoma de Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe impact of hospital emergency care and inward admission for acute exacerbations of COPD on inhaled maintenance treatment is not well known.

objectiveTherefore, we evaluated the impact of short-stay emergency hospital care and inward admission for acute exacerbation of COPD (eCOPD) on inhaled maintenance treatment prescribed at discharge.

designProspective observational cohort study of patients presenting with eCOPD at emergency departments in 16 hospitals of the Spanish healthcare system. The ethics committee at each hospital approved the study and patients provided an informed consent before inclusion. We classified the patients according to the severity of COPD: mild/moderate (FEV1 ≥ 50% predicted) or severe/very severe (FEV1 < 50% predicted) and need of inward hospitalisation. We analysed changes to maintenance treatment on discharge according to GOLD strategy.

results1559 patients, 65% required hospitalisation. The most common maintenance treatment was inhaled corticoids (ICS) (80.9%) followed by long-acting beta-agonists (LABA) (75.4%). The most common combination was triple therapy (LABA+ LAMA+ICS) (56.2%) followed by LABA+ICS dual therapy (18.2%) regardless of the severity of COPD. In more than 60% of patients treatment was not changed at discharge. The most common change in treatment was a reduction when discharge was from emergency care and an increase after hospitalisation (-21.6% and +19.5% in severe/very severe COPD, respectively).

conclusionsEmergency hospital care for eCOPD does not usually induce changes in inhaled maintenance treatment for COPD regardless of the duration of the hospital stay.

Indexed as

Emergency Service, HospitalHospitalizationAdministration, InhalationAdrenergic beta-AgonistsAgedAged, 80 and overCohort StudiesDisease ProgressionEmergenciesFemaleForced Expiratory VolumeGlucocorticoidsHospitals, PublicHumansLength of StayMaintenance ChemotherapyAdrenergic beta-AgonistsGlucocorticoidsMuscarinic Antagonistsclinical practiceinward admissionquality of caretriple therapy

Identifiers

PMID26417965
OpenAlexW1951681830

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.