Evidence map›Paper›PMID 26417528›Full record

ArticleBiomedical optics express2015

Direct regularization from co-registered anatomical images for MRI-guided near-infrared spectral tomographic image reconstruction.

Limin Zhang, Yan Zhao, Shudong Jiang, Brian W Pogue, Keith D Paulsen

Abstract read
In one paragraph

Article in Biomedical optics express, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

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  9. Enhanced diffuse optical tomographic reconstruction using concurrent ultrasound information.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Limin ZhangThayer School of Engineering, Dartmouth College, Hanover NH 03755, USA ; College of Precision Instrument and Optoelectronics Engineering, Tianjin University, Tianjin 300072, China ; Tianjin Key Laboratory of Biomedical Detecting Techniques and Instrument, Tianjin 300072, China.
Yan ZhaoThayer School of Engineering, Dartmouth College, Hanover NH 03755, USA.
Shudong JiangThayer School of Engineering, Dartmouth College, Hanover NH 03755, USA.
Brian W PogueThayer School of Engineering, Dartmouth College, Hanover NH 03755, USA.
Keith D PaulsenThayer School of Engineering, Dartmouth College, Hanover NH 03755, USA.

Funding

Concurrent Optical Spectroscopy and Breast MRI to Improve Diagnosis without Contrast InjectionR01EB027098 · NIBIB · DARTMOUTH COLLEGE · PI Shudong Jiang, KEITH D. PAULSEN · 2019 to 2026
$3.3M
FREQUENCY DOMAIN OPTICAL IMAGING OF BREAST CANCERR01CA069544 · NCI · DARTMOUTH COLLEGE · PI PAULSEN, KEITH D. · 1996 to 2012
$2.4M
Monitoring Neoadjuvant Chemotherapy Responses with NIR TomographyR01CA176086 · NCI · DARTMOUTH COLLEGE · PI JIANG, SHUDONG · 2014 to 2018
$2.0M
NIRFASTR01CA132750 · NCI · DARTMOUTH COLLEGE · PI POGUE, BRIAN WILLIAM · 2009 to 2012
$1.2M
NCI NIH HHS R01 CA069544NCI NIH HHS R01 CA176086NIBIB NIH HHS R01 EB027098
6 · The paper itself

Abstract

Combining anatomical information from high resolution imaging modalities to guide near-infrared spectral tomography (NIRST) is an efficient strategy for improving the quality of the reconstructed spectral images. A new approach for incorporating image information directly into the inversion matrix regularization was examined using Direct Regularization from Images (DRI), which encodes the gray-scale data into the NIRST image reconstruction problem. This process has the benefit of eliminating user intervention such as image segmentation of distinct regions. Specifically, the Dynamic Contrast Enhanced Magnetic Resonance (DCE-MR) image intensity value differences within the anatomical image were used to implement an exponentially-weighted regularization function between the image pixels. The algorithm was validated using simulated reconstructions with noise, and the results showed that spatial resolution and robustness of the reconstructed images were significantly improved by appropriate choice of the regularization weight parameters. The proposed approach was also tested on in vivo breast data acquired in a recent clinical trial combining NIRST / MRI for cancer tumor characterization. Relative to the standard "no priors" diffuse recovery, the contrast of the tumor to the normal surrounding tissue increased from 2.4 to 3.6, and the difference between the tumor size segmented from DCE-MR images and reconstructed optical images decreased from 18% to 6%, while there was an overall decrease in surface artifacts.

Indexed as

(100.3010) Image reconstruction techniques(170.3880) Medical and biological imaging(170.6960) Tomography

Identifiers

PMID26417528
PMCPMC4574684

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.