Evidence map›Paper›PMID 26417495›Full record

ArticleBiomedical optics express2015

Photoacoustic imaging of cerebral hypoperfusion during acupuncture.

B Z Chen, J G Yang, D Wu, D W Zeng, Y Yi, N Yang, H B Jiang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedical optics express, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

B Z ChenSchool of Physical Electronics, University of Electronic Science and Technology of China, Chengdu, 610054, China.
J G YangSchool of Physical Electronics, University of Electronic Science and Technology of China, Chengdu, 610054, China.
D WuSchool of Physical Electronics, University of Electronic Science and Technology of China, Chengdu, 610054, China.
D W ZengInstitute of Laboratory Animals of Sichuan Academy of Medical Sciences and Sichuan Province People's Hospital, Chengdu, 610054, China.
Y YiInstitute of Laboratory Animals of Sichuan Academy of Medical Sciences and Sichuan Province People's Hospital, Chengdu, 610054, China.
N YangInstitute of Laboratory Animals of Sichuan Academy of Medical Sciences and Sichuan Province People's Hospital, Chengdu, 610054, China.
H B JiangSchool of Physical Electronics, University of Electronic Science and Technology of China, Chengdu, 610054, China ; Department of Biomedical Engineering, University of Florida, Gainesville, FL 32611, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Using acupuncture to treat cerebral hypoperfusion is a hot topic. However, there is a lack of effective tools to clarify the therapeutic effect of acupuncture on cerebral hypoperfusion. Here, we show in a mouse model of cerebral hypoperfusion that photoacoustic tomography (PAT) can noninvasively image cerebral vasculature and track total hemoglobin (HbT) concentration changes in cerebral hypoperfusion with acupuncture stimulation on the YangLingQuan (GB34) point. We measured the changes of HbT concentration and found that the HbT concentration in hypoperfusion regions was clearly lower than that in the control regions when the acupuncture was absent; however, it was significantly increased when the acupuncture was implemented on the GB34 point. We also observed the increase of vessel size and the generation of new vessels in cerebral hypoperfusion during acupuncture. Laser speckle imaging (LSI) was employed to validate some of the PAT findings.

Indexed as

(170.2655) Functional monitoring and imaging(170.5120) Photoacoustic imaging

Identifiers

PMID26417495
PMCPMC4574651

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.