ArticlePlant physiology2015
Repression of Lateral Organ Boundary Genes by PENNYWISE and POUND-FOOLISH Is Essential for Meristem Maintenance and Flowering in Arabidopsis.
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Article in Plant physiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
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46 citing papers in PubMed, 66 citations in OpenAlex.
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- Rice Transcription Factor HSTL Regulates Plant Height and Salt Stress Response by Modulating Gibberellin Homeostasis.Rice (New York, N.Y.) · 2025Article
- Abscission zones: cellular interfaces for the programmed separation of organs.Annals of botany · 2025Review
- The transcriptional regulator VAL1 promotes Arabidopsis flowering by repressing the organ boundary genes BOP1 and BOP2.Plant physiology · 2025Article
- Regulation of meristem and hormone function revealed through analysis of directly-regulated SHOOT MERISTEMLESS target genes.Scientific reports · 2025Article
- Identification of QTLs for early maturity-related traits based on RIL population of two elite cotton cultivars.BMC plant biology · 2024Article
- Transcriptome Profiling Reveals Key Regulatory Networks for Age-Dependent Vernalization in Welsh Onion (International journal of molecular sciences · 2024Article
- Abscission in plants: from mechanism to applications.Advanced biotechnology · 2024Review
- A quantitative gibberellin signaling biosensor reveals a role for gibberellins in internode specification at the shoot apical meristem.Nature communications · 2024Article
- Interaction among homeodomain transcription factors mediates ethylene biosynthesis during pear fruit ripening.Horticulture research · 2024Article
- BEL transcription factors in prominent Solanaceae crops: the missing pieces of the jigsaw in plant development.Planta · 2023Review
- SQUAMOSA PROMOTER BINDING PROTEIN-LIKE 9 and 13 repress BLADE-ON-PETIOLE 1 and 2 directly to promote adult leaf morphology in Arabidopsis.Journal of experimental botany · 2023Article
- Regulation of secondary growth by poplarFrontiers in plant science · 2023Article
- Flower Development in Arabidopsis.Methods in molecular biology (Clifton, N.J.) · 2023Article
- Genome-wide characterization of the TALE homeodomain family and the KNOX-BLH interaction network in tomato.Plant molecular biology · 2022Article
- The Roles of BLH Transcription Factors in Plant Development and Environmental Response.International journal of molecular sciences · 2022Review
- Brachypodium distachyon UNICULME4 and LAXATUM-A are redundantly required for development.Plant physiology · 2022Article
- MdNup54 Interactions With MdHSP70 Involved in Flowering in Apple.Frontiers in plant science · 2022Article
- The flowering transition pathways converge into a complex gene regulatory network that underlies the phase changes of the shoot apical meristem inFrontiers in plant science · 2022Article
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Authors and funding
17 authors at 8 institutions in 3 countries.
Madiha KhanDepartment of Biology, Carleton University, Ottawa, Ontario, Canada K1S 5B6 (M.K., P.T., B.C.S., S.Ch., J.L., S.R.H.);Institut Jean-Pierre Bourgin, Unité Mixte de Recherche 1318 Institut National de la Recherche Agronomique-AgroParisTech, Bâtiment 2, Institut National de la Recherche Agronomique Centre de Versailles-Grignon, 78026 Versailles cedex, France (L.R., H.M., J.-P.R., S.Ci., V.P.); Plant Biotechnology Institute,National Research Council Canada, Saskatoon, Saskatchewan, Canada S7N 0W9 (R.D., C.Y., D.X.);Department of Biological Sciences, Brock University, St. Catharines, Ontario, Canada L2S 3A1 (X.K, C.D.); andMolecular Plant Physiology, Department of Biology, Faculty of Sciences, Utrecht University, CH-3584 Utrecht, The Netherlands (M.P.).
Laura RagniDepartment of Biology, Carleton University, Ottawa, Ontario, Canada K1S 5B6 (M.K., P.T., B.C.S., S.Ch., J.L., S.R.H.);Institut Jean-Pierre Bourgin, Unité Mixte de Recherche 1318 Institut National de la Recherche Agronomique-AgroParisTech, Bâtiment 2, Institut National de la Recherche Agronomique Centre de Versailles-Grignon, 78026 Versailles cedex, France (L.R., H.M., J.-P.R., S.Ci., V.P.); Plant Biotechnology Institute,National Research Council Canada, Saskatoon, Saskatchewan, Canada S7N 0W9 (R.D., C.Y., D.X.);Department of Biological Sciences, Brock University, St. Catharines, Ontario, Canada L2S 3A1 (X.K, C.D.); andMolecular Plant Physiology, Department of Biology, Faculty of Sciences, Utrecht University, CH-3584 Utrecht, The Netherlands (M.P.).
Paul TabbDepartment of Biology, Carleton University, Ottawa, Ontario, Canada K1S 5B6 (M.K., P.T., B.C.S., S.Ch., J.L., S.R.H.);Institut Jean-Pierre Bourgin, Unité Mixte de Recherche 1318 Institut National de la Recherche Agronomique-AgroParisTech, Bâtiment 2, Institut National de la Recherche Agronomique Centre de Versailles-Grignon, 78026 Versailles cedex, France (L.R., H.M., J.-P.R., S.Ci., V.P.); Plant Biotechnology Institute,National Research Council Canada, Saskatoon, Saskatchewan, Canada S7N 0W9 (R.D., C.Y., D.X.);Department of Biological Sciences, Brock University, St. Catharines, Ontario, Canada L2S 3A1 (X.K, C.D.); andMolecular Plant Physiology, Department of Biology, Faculty of Sciences, Utrecht University, CH-3584 Utrecht, The Netherlands (M.P.).
Brenda C SalasiniDepartment of Biology, Carleton University, Ottawa, Ontario, Canada K1S 5B6 (M.K., P.T., B.C.S., S.Ch., J.L., S.R.H.);Institut Jean-Pierre Bourgin, Unité Mixte de Recherche 1318 Institut National de la Recherche Agronomique-AgroParisTech, Bâtiment 2, Institut National de la Recherche Agronomique Centre de Versailles-Grignon, 78026 Versailles cedex, France (L.R., H.M., J.-P.R., S.Ci., V.P.); Plant Biotechnology Institute,National Research Council Canada, Saskatoon, Saskatchewan, Canada S7N 0W9 (R.D., C.Y., D.X.);Department of Biological Sciences, Brock University, St. Catharines, Ontario, Canada L2S 3A1 (X.K, C.D.); andMolecular Plant Physiology, Department of Biology, Faculty of Sciences, Utrecht University, CH-3584 Utrecht, The Netherlands (M.P.).ORCID http://orcid.org/0000-0002-0050-4001
Steven ChatfieldDepartment of Biology, Carleton University, Ottawa, Ontario, Canada K1S 5B6 (M.K., P.T., B.C.S., S.Ch., J.L., S.R.H.);Institut Jean-Pierre Bourgin, Unité Mixte de Recherche 1318 Institut National de la Recherche Agronomique-AgroParisTech, Bâtiment 2, Institut National de la Recherche Agronomique Centre de Versailles-Grignon, 78026 Versailles cedex, France (L.R., H.M., J.-P.R., S.Ci., V.P.); Plant Biotechnology Institute,National Research Council Canada, Saskatoon, Saskatchewan, Canada S7N 0W9 (R.D., C.Y., D.X.);Department of Biological Sciences, Brock University, St. Catharines, Ontario, Canada L2S 3A1 (X.K, C.D.); andMolecular Plant Physiology, Department of Biology, Faculty of Sciences, Utrecht University, CH-3584 Utrecht, The Netherlands (M.P.).
Raju DatlaDepartment of Biology, Carleton University, Ottawa, Ontario, Canada K1S 5B6 (M.K., P.T., B.C.S., S.Ch., J.L., S.R.H.);Institut Jean-Pierre Bourgin, Unité Mixte de Recherche 1318 Institut National de la Recherche Agronomique-AgroParisTech, Bâtiment 2, Institut National de la Recherche Agronomique Centre de Versailles-Grignon, 78026 Versailles cedex, France (L.R., H.M., J.-P.R., S.Ci., V.P.); Plant Biotechnology Institute,National Research Council Canada, Saskatoon, Saskatchewan, Canada S7N 0W9 (R.D., C.Y., D.X.);Department of Biological Sciences, Brock University, St. Catharines, Ontario, Canada L2S 3A1 (X.K, C.D.); andMolecular Plant Physiology, Department of Biology, Faculty of Sciences, Utrecht University, CH-3584 Utrecht, The Netherlands (M.P.).
John LockDepartment of Biology, Carleton University, Ottawa, Ontario, Canada K1S 5B6 (M.K., P.T., B.C.S., S.Ch., J.L., S.R.H.);Institut Jean-Pierre Bourgin, Unité Mixte de Recherche 1318 Institut National de la Recherche Agronomique-AgroParisTech, Bâtiment 2, Institut National de la Recherche Agronomique Centre de Versailles-Grignon, 78026 Versailles cedex, France (L.R., H.M., J.-P.R., S.Ci., V.P.); Plant Biotechnology Institute,National Research Council Canada, Saskatoon, Saskatchewan, Canada S7N 0W9 (R.D., C.Y., D.X.);Department of Biological Sciences, Brock University, St. Catharines, Ontario, Canada L2S 3A1 (X.K, C.D.); andMolecular Plant Physiology, Department of Biology, Faculty of Sciences, Utrecht University, CH-3584 Utrecht, The Netherlands (M.P.).ORCID http://orcid.org/0000-0002-3526-7982
Xiahezi KuaiDepartment of Biology, Carleton University, Ottawa, Ontario, Canada K1S 5B6 (M.K., P.T., B.C.S., S.Ch., J.L., S.R.H.);Institut Jean-Pierre Bourgin, Unité Mixte de Recherche 1318 Institut National de la Recherche Agronomique-AgroParisTech, Bâtiment 2, Institut National de la Recherche Agronomique Centre de Versailles-Grignon, 78026 Versailles cedex, France (L.R., H.M., J.-P.R., S.Ci., V.P.); Plant Biotechnology Institute,National Research Council Canada, Saskatoon, Saskatchewan, Canada S7N 0W9 (R.D., C.Y., D.X.);Department of Biological Sciences, Brock University, St. Catharines, Ontario, Canada L2S 3A1 (X.K, C.D.); andMolecular Plant Physiology, Department of Biology, Faculty of Sciences, Utrecht University, CH-3584 Utrecht, The Netherlands (M.P.).
Charles DesprésDepartment of Biology, Carleton University, Ottawa, Ontario, Canada K1S 5B6 (M.K., P.T., B.C.S., S.Ch., J.L., S.R.H.);Institut Jean-Pierre Bourgin, Unité Mixte de Recherche 1318 Institut National de la Recherche Agronomique-AgroParisTech, Bâtiment 2, Institut National de la Recherche Agronomique Centre de Versailles-Grignon, 78026 Versailles cedex, France (L.R., H.M., J.-P.R., S.Ci., V.P.); Plant Biotechnology Institute,National Research Council Canada, Saskatoon, Saskatchewan, Canada S7N 0W9 (R.D., C.Y., D.X.);Department of Biological Sciences, Brock University, St. Catharines, Ontario, Canada L2S 3A1 (X.K, C.D.); andMolecular Plant Physiology, Department of Biology, Faculty of Sciences, Utrecht University, CH-3584 Utrecht, The Netherlands (M.P.).
Marcel ProveniersDepartment of Biology, Carleton University, Ottawa, Ontario, Canada K1S 5B6 (M.K., P.T., B.C.S., S.Ch., J.L., S.R.H.);Institut Jean-Pierre Bourgin, Unité Mixte de Recherche 1318 Institut National de la Recherche Agronomique-AgroParisTech, Bâtiment 2, Institut National de la Recherche Agronomique Centre de Versailles-Grignon, 78026 Versailles cedex, France (L.R., H.M., J.-P.R., S.Ci., V.P.); Plant Biotechnology Institute,National Research Council Canada, Saskatoon, Saskatchewan, Canada S7N 0W9 (R.D., C.Y., D.X.);Department of Biological Sciences, Brock University, St. Catharines, Ontario, Canada L2S 3A1 (X.K, C.D.); andMolecular Plant Physiology, Department of Biology, Faculty of Sciences, Utrecht University, CH-3584 Utrecht, The Netherlands (M.P.).ORCID http://orcid.org/0000-0001-7896-6049
Cao YongguoDepartment of Biology, Carleton University, Ottawa, Ontario, Canada K1S 5B6 (M.K., P.T., B.C.S., S.Ch., J.L., S.R.H.);Institut Jean-Pierre Bourgin, Unité Mixte de Recherche 1318 Institut National de la Recherche Agronomique-AgroParisTech, Bâtiment 2, Institut National de la Recherche Agronomique Centre de Versailles-Grignon, 78026 Versailles cedex, France (L.R., H.M., J.-P.R., S.Ci., V.P.); Plant Biotechnology Institute,National Research Council Canada, Saskatoon, Saskatchewan, Canada S7N 0W9 (R.D., C.Y., D.X.);Department of Biological Sciences, Brock University, St. Catharines, Ontario, Canada L2S 3A1 (X.K, C.D.); andMolecular Plant Physiology, Department of Biology, Faculty of Sciences, Utrecht University, CH-3584 Utrecht, The Netherlands (M.P.).
Daoquan XiangDepartment of Biology, Carleton University, Ottawa, Ontario, Canada K1S 5B6 (M.K., P.T., B.C.S., S.Ch., J.L., S.R.H.);Institut Jean-Pierre Bourgin, Unité Mixte de Recherche 1318 Institut National de la Recherche Agronomique-AgroParisTech, Bâtiment 2, Institut National de la Recherche Agronomique Centre de Versailles-Grignon, 78026 Versailles cedex, France (L.R., H.M., J.-P.R., S.Ci., V.P.); Plant Biotechnology Institute,National Research Council Canada, Saskatoon, Saskatchewan, Canada S7N 0W9 (R.D., C.Y., D.X.);Department of Biological Sciences, Brock University, St. Catharines, Ontario, Canada L2S 3A1 (X.K, C.D.); andMolecular Plant Physiology, Department of Biology, Faculty of Sciences, Utrecht University, CH-3584 Utrecht, The Netherlands (M.P.).ORCID http://orcid.org/0000-0001-7144-1274
Halima MorinDepartment of Biology, Carleton University, Ottawa, Ontario, Canada K1S 5B6 (M.K., P.T., B.C.S., S.Ch., J.L., S.R.H.);Institut Jean-Pierre Bourgin, Unité Mixte de Recherche 1318 Institut National de la Recherche Agronomique-AgroParisTech, Bâtiment 2, Institut National de la Recherche Agronomique Centre de Versailles-Grignon, 78026 Versailles cedex, France (L.R., H.M., J.-P.R., S.Ci., V.P.); Plant Biotechnology Institute,National Research Council Canada, Saskatoon, Saskatchewan, Canada S7N 0W9 (R.D., C.Y., D.X.);Department of Biological Sciences, Brock University, St. Catharines, Ontario, Canada L2S 3A1 (X.K, C.D.); andMolecular Plant Physiology, Department of Biology, Faculty of Sciences, Utrecht University, CH-3584 Utrecht, The Netherlands (M.P.).
Jean-Pierre RullièreDepartment of Biology, Carleton University, Ottawa, Ontario, Canada K1S 5B6 (M.K., P.T., B.C.S., S.Ch., J.L., S.R.H.);Institut Jean-Pierre Bourgin, Unité Mixte de Recherche 1318 Institut National de la Recherche Agronomique-AgroParisTech, Bâtiment 2, Institut National de la Recherche Agronomique Centre de Versailles-Grignon, 78026 Versailles cedex, France (L.R., H.M., J.-P.R., S.Ci., V.P.); Plant Biotechnology Institute,National Research Council Canada, Saskatoon, Saskatchewan, Canada S7N 0W9 (R.D., C.Y., D.X.);Department of Biological Sciences, Brock University, St. Catharines, Ontario, Canada L2S 3A1 (X.K, C.D.); andMolecular Plant Physiology, Department of Biology, Faculty of Sciences, Utrecht University, CH-3584 Utrecht, The Netherlands (M.P.).
Sylvie CiterneDepartment of Biology, Carleton University, Ottawa, Ontario, Canada K1S 5B6 (M.K., P.T., B.C.S., S.Ch., J.L., S.R.H.);Institut Jean-Pierre Bourgin, Unité Mixte de Recherche 1318 Institut National de la Recherche Agronomique-AgroParisTech, Bâtiment 2, Institut National de la Recherche Agronomique Centre de Versailles-Grignon, 78026 Versailles cedex, France (L.R., H.M., J.-P.R., S.Ci., V.P.); Plant Biotechnology Institute,National Research Council Canada, Saskatoon, Saskatchewan, Canada S7N 0W9 (R.D., C.Y., D.X.);Department of Biological Sciences, Brock University, St. Catharines, Ontario, Canada L2S 3A1 (X.K, C.D.); andMolecular Plant Physiology, Department of Biology, Faculty of Sciences, Utrecht University, CH-3584 Utrecht, The Netherlands (M.P.).ORCID http://orcid.org/0000-0001-5026-095X
Shelley R HepworthDepartment of Biology, Carleton University, Ottawa, Ontario, Canada K1S 5B6 (M.K., P.T., B.C.S., S.Ch., J.L., S.R.H.);Institut Jean-Pierre Bourgin, Unité Mixte de Recherche 1318 Institut National de la Recherche Agronomique-AgroParisTech, Bâtiment 2, Institut National de la Recherche Agronomique Centre de Versailles-Grignon, 78026 Versailles cedex, France (L.R., H.M., J.-P.R., S.Ci., V.P.); Plant Biotechnology Institute,National Research Council Canada, Saskatoon, Saskatchewan, Canada S7N 0W9 (R.D., C.Y., D.X.);Department of Biological Sciences, Brock University, St. Catharines, Ontario, Canada L2S 3A1 (X.K, C.D.); andMolecular Plant Physiology, Department of Biology, Faculty of Sciences, Utrecht University, CH-3584 Utrecht, The Netherlands (M.P.) shelley_hepworth@carleton.ca pautot@versailles.inra.fr.ORCID http://orcid.org/0000-0002-6496-3792
Véronique PautotDepartment of Biology, Carleton University, Ottawa, Ontario, Canada K1S 5B6 (M.K., P.T., B.C.S., S.Ch., J.L., S.R.H.);Institut Jean-Pierre Bourgin, Unité Mixte de Recherche 1318 Institut National de la Recherche Agronomique-AgroParisTech, Bâtiment 2, Institut National de la Recherche Agronomique Centre de Versailles-Grignon, 78026 Versailles cedex, France (L.R., H.M., J.-P.R., S.Ci., V.P.); Plant Biotechnology Institute,National Research Council Canada, Saskatoon, Saskatchewan, Canada S7N 0W9 (R.D., C.Y., D.X.);Department of Biological Sciences, Brock University, St. Catharines, Ontario, Canada L2S 3A1 (X.K, C.D.); andMolecular Plant Physiology, Department of Biology, Faculty of Sciences, Utrecht University, CH-3584 Utrecht, The Netherlands (M.P.) shelley_hepworth@carleton.ca pautot@versailles.inra.fr.ORCID http://orcid.org/0000-0003-1808-5172
Carleton University · CAPlant Biotechnology Institute · CABrock University · CASaskatchewan Research Council (Canada) · CAAgroParisTech · FRInstitut Jean-Pierre Bourgin · FRNational Research Council Canada · CAUtrecht University · NL
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the model plant Arabidopsis (Arabidopsis thaliana), endogenous and environmental signals acting on the shoot apical meristem cause acquisition of inflorescence meristem fate. This results in changed patterns of aerial development seen as the transition from making leaves to the production of flowers separated by elongated internodes. Two related BEL1-like homeobox genes, PENNYWISE (PNY) and POUND-FOOLISH (PNF), fulfill this transition. Loss of function of these genes impairs stem cell maintenance and blocks internode elongation and flowering. We show here that pny pnf apices misexpress lateral organ boundary genes BLADE-ON-PETIOLE1/2 (BOP1/2) and KNOTTED-LIKE FROM ARABIDOPSIS THALIANA6 (KNAT6) together with ARABIDOPSIS THALIANA HOMEOBOX GENE1 (ATH1). Inactivation of genes in this module fully rescues pny pnf defects. We further show that BOP1 directly activates ATH1, whereas activation of KNAT6 is indirect. The pny pnf restoration correlates with renewed accumulation of transcripts conferring floral meristem identity, including FD, SQUAMOSA PROMOTER-BINDING PROTEIN LIKE genes, LEAFY, and APETALA1. To gain insight into how this module blocks flowering, we analyzed the transcriptome of BOP1-overexpressing plants. Our data suggest a central role for the microRNA156-SQUAMOSA PROMOTER BINDING PROTEIN-LIKE-microRNA172 module in integrating stress signals conferred in part by promotion of jasmonic acid biosynthesis. These data reveal a potential mechanism by which repression of lateral organ boundary genes by PNY-PNF is essential for flowering.
Indexed as
Gene Expression Regulation, PlantArabidopsisArabidopsis ProteinsCyclopentanesFlowersHomeodomain ProteinsMeristemMicroRNAsMutationNuclear ProteinsOxylipinsPlant Growth RegulatorsRepressor ProteinsReproductionSignal TransductionArabidopsis ProteinsBOP1 protein, ArabidopsisBOP2 protein, ArabidopsisCyclopentanesHomeodomain Proteinsjasmonic acidMicroRNAsMirn156 microRNA, ArabidopsisMirn172 microRNA, ArabidopsisNuclear ProteinsOxylipinsPlant Growth RegulatorsPNF protein, ArabidopsisRepressor ProteinsRPL protein, ArabidopsisSPL protein, Arabidopsis
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