ArticleAntimicrobial agents and chemotherapy2015
Fitness Studies of Azole-Resistant Strains of Aspergillus fumigatus.
Article in Antimicrobial agents and chemotherapy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- CYP51C Y319H and H349R substitutions cannot confer azole resistance inMicrobiology spectrum · 2026Article
- Article
- Adaptation Under Pressure: Resistance and Stress Response Interplay in ClinicalJournal of fungi (Basel, Switzerland) · 2025Article
- Review
- Assessing fitness costs in malaria parasites: a comprehensive review and implications for drug resistance management.Malaria journal · 2025Review
- Most azole resistance mutations in the Candida albicans drug target confer cross-resistance without intrinsic fitness cost.Nature microbiology · 2024Article
- Triazole resistance inApplied and environmental microbiology · 2024Article
- Article
- Quantitative PCR Effectively Quantifies Triazole-Susceptible and Triazole-ResistantJournal of fungi (Basel, Switzerland) · 2022Article
- Novel Treatment Approach for Aspergilloses by Targeting Germination.Journal of fungi (Basel, Switzerland) · 2022Review
- Assessing Differences between Clinical Isolates ofPathogens (Basel, Switzerland) · 2022Article
- Phylogenetic Distribution ofMicrobiology spectrum · 2021Article
- In Vivo Efficacy of Voriconazole in aJournal of fungi (Basel, Switzerland) · 2021Article
- Review
- Clinical and experimental phenotype of azole-resistant Aspergillus fumigatus with a HapE splice site mutation: a case report.BMC infectious diseases · 2021Article
- Aspergillus fumigatus and Aspergillosis in 2019.Clinical microbiology reviews · 2019Review
- In-host microevolution of Aspergillus fumigatus: A phenotypic and genotypic analysis.Fungal genetics and biology : FG & B · 2018Article
- Molecular Tools for the Detection and Deduction of Azole Antifungal Drug Resistance Phenotypes in Aspergillus Species.Clinical microbiology reviews · 2017Review
- Ecology of aspergillosis: insights into the pathogenic potency of Aspergillus fumigatus and some other Aspergillus species.Microbial biotechnology · 2017Review
- Clinical implications of globally emerging azole resistance in Aspergillus fumigatus.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2016Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Isogenic bar-coded strains of Aspergillus fumigatus carrying the G54W or M220K mutation in Cyp51A were constructed. In vitro, the growth and conidiation capacities of the mutants were similar to those of the parental strain. Competition studies in the absence of azoles showed that there was no adverse fitness cost for the azole-resistant A. fumigatus strains in vitro or in vivo compared to the parental strain.
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Registered trials
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