Evidence map›Paper›PMID 26416105›Full record

ArticleThe American journal of tropical medicine and hygiene2015

Rapid Tests and the Diagnosis of Visceral Leishmaniasis and Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome Coinfection.

Walter Lins Barbosa Júnior, Paulo Sérgio Ramos de Araújo, Luiz Dias de Andrade, Ana Maria Aguiar Dos Santos, Maria Almerice Lopes da Silva, Filipe Dantas-Torres, Zulma Medeiros

Open access · bronzeAbstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Diagnosis and Causative Species of Visceral Leishmaniasis in Southwest Saudi Arabia.The American journal of tropical medicine and hygiene · 2021
    Article
  6. Review
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  10. Leishmaniasis diagnosis: an update on the use of parasitological, immunological and molecular methods.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2020
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Walter Lins Barbosa JúniorDepartment of Parasitology, Centro de Pesquisas Aggeu Magalhães, Fundação Oswaldo Cruz, Pernambuco, Brazil; Hospital das Clínicas, Universidade Federal de Pernambuco, Pernambuco, Brazil; Instituto de Ciências Biológicas, Universidade de Pernambuco, Pernambuco, Brazil; Department of Immunology, Centro de Pesquisas Aggeu Magalhães, Fundação Oswaldo Cruz, Pernambuco, Brazil; Department of Veterinary Medicine, Universitá degli Studi di Bari, Bari, Italy walterb716@gmail.com.
Paulo Sérgio Ramos de AraújoDepartment of Parasitology, Centro de Pesquisas Aggeu Magalhães, Fundação Oswaldo Cruz, Pernambuco, Brazil; Hospital das Clínicas, Universidade Federal de Pernambuco, Pernambuco, Brazil; Instituto de Ciências Biológicas, Universidade de Pernambuco, Pernambuco, Brazil; Department of Immunology, Centro de Pesquisas Aggeu Magalhães, Fundação Oswaldo Cruz, Pernambuco, Brazil; Department of Veterinary Medicine, Universitá degli Studi di Bari, Bari, Italy.
Luiz Dias de AndradeDepartment of Parasitology, Centro de Pesquisas Aggeu Magalhães, Fundação Oswaldo Cruz, Pernambuco, Brazil; Hospital das Clínicas, Universidade Federal de Pernambuco, Pernambuco, Brazil; Instituto de Ciências Biológicas, Universidade de Pernambuco, Pernambuco, Brazil; Department of Immunology, Centro de Pesquisas Aggeu Magalhães, Fundação Oswaldo Cruz, Pernambuco, Brazil; Department of Veterinary Medicine, Universitá degli Studi di Bari, Bari, Italy.
Ana Maria Aguiar Dos SantosDepartment of Parasitology, Centro de Pesquisas Aggeu Magalhães, Fundação Oswaldo Cruz, Pernambuco, Brazil; Hospital das Clínicas, Universidade Federal de Pernambuco, Pernambuco, Brazil; Instituto de Ciências Biológicas, Universidade de Pernambuco, Pernambuco, Brazil; Department of Immunology, Centro de Pesquisas Aggeu Magalhães, Fundação Oswaldo Cruz, Pernambuco, Brazil; Department of Veterinary Medicine, Universitá degli Studi di Bari, Bari, Italy.
Maria Almerice Lopes da SilvaDepartment of Parasitology, Centro de Pesquisas Aggeu Magalhães, Fundação Oswaldo Cruz, Pernambuco, Brazil; Hospital das Clínicas, Universidade Federal de Pernambuco, Pernambuco, Brazil; Instituto de Ciências Biológicas, Universidade de Pernambuco, Pernambuco, Brazil; Department of Immunology, Centro de Pesquisas Aggeu Magalhães, Fundação Oswaldo Cruz, Pernambuco, Brazil; Department of Veterinary Medicine, Universitá degli Studi di Bari, Bari, Italy.
Filipe Dantas-TorresDepartment of Parasitology, Centro de Pesquisas Aggeu Magalhães, Fundação Oswaldo Cruz, Pernambuco, Brazil; Hospital das Clínicas, Universidade Federal de Pernambuco, Pernambuco, Brazil; Instituto de Ciências Biológicas, Universidade de Pernambuco, Pernambuco, Brazil; Department of Immunology, Centro de Pesquisas Aggeu Magalhães, Fundação Oswaldo Cruz, Pernambuco, Brazil; Department of Veterinary Medicine, Universitá degli Studi di Bari, Bari, Italy.
Zulma MedeirosDepartment of Parasitology, Centro de Pesquisas Aggeu Magalhães, Fundação Oswaldo Cruz, Pernambuco, Brazil; Hospital das Clínicas, Universidade Federal de Pernambuco, Pernambuco, Brazil; Instituto de Ciências Biológicas, Universidade de Pernambuco, Pernambuco, Brazil; Department of Immunology, Centro de Pesquisas Aggeu Magalhães, Fundação Oswaldo Cruz, Pernambuco, Brazil; Department of Veterinary Medicine, Universitá degli Studi di Bari, Bari, Italy.
Universidade de Pernambuco · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

After the emergence of the human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS), the number of visceral leishmaniasis (VL)-HIV/AIDS coinfections has increased worldwide. Herein, we assessed the usefulness of an rK39-based immunochromatographic test (rK39 ICT) (DiaMed-IT LEISH(®); DiaMed AG, Cressier-sur-Morat, Switzerland) and a latex agglutination test (KAtex; Kalon Biological, Guildford, United Kingdom) for urinary antigen detection to diagnose VL in 15 HIV/AIDS patients from northeastern Brazil. VL diagnosis was based on clinical findings, cytology, serology, parasite DNA, and/or urinary antigen detection. VL was confirmed in seven out of 15 HIV/AIDS patients. Only three patients were positive in bone marrow cytology, three patients were conventional polymerase chain reaction (PCR) positive, while six were real-time PCR positive. All patients were direct agglutination test (DAT) (Royal Tropical Institute, Amsterdam, The Netherlands) positive; of these, four were positive by rK39 ICT and five by KAtex. Large-scale studies are needed to validate the use of the KAtex in the national public health laboratory network in Brazil, aiming at improving the diagnosis of VL in HIV/AIDS patients in this country.

Indexed as

AdultAgglutination TestsAntigens, ProtozoanBiomarkersChromatography, AffinityCoinfectionFemaleHIV InfectionsHumansLatex Fixation TestsLeishmaniasis, VisceralMaleMiddle AgedProtozoan ProteinsReproducibility of ResultsSensitivity and SpecificityAntigens, ProtozoanBiomarkersK39 antigen, LeishmaniaProtozoan Proteins

Identifiers

PMID26416105
PMCPMC4703249
OpenAlexW2298597695

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.