ArticleJournal of magnetic resonance (San Diego, Calif. : 1997)2015
Imaging disulfide dinitroxides at 250 MHz to monitor thiol redox status.
Article in Journal of magnetic resonance (San Diego, Calif. : 1997), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Field-domain rapid-scan EPR at 240GHz for studies of protein functional dynamics at room temperature.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2024Article
- In Vivo Electron Paramagnetic Resonance Molecular Profiling of Tumor Microenvironment upon Tumor Progression to Malignancy in an Animal Model of Breast Cancer.Molecular imaging and biology · 2024Article
- Direct Measurement and Imaging of Redox Status with Electron Paramagnetic Resonance.Antioxidants & redox signaling · 2024Article
- Cyclic Disulfide-Bridged Dinitroxide Biradical for Measuring Thiol Redox Status by Electron Paramagnetic Resonance.The journal of physical chemistry. B · 2023Article
- Redox-Sensitive Mapping of a Mouse Tumor Model Using Sparse Projection Sampling of Electron Paramagnetic Resonance.Antioxidants & redox signaling · 2022Article
- EPR Everywhere.Applied magnetic resonance · 2021Review
- Rapid-scan EPR imaging of a phantom comprised of species with different linewidths and relaxation times.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2019Article
- Use of Electron Paramagnetic Resonance in Biological Samples at Ambient Temperature and 77 K.Journal of visualized experiments : JoVE · 2019Article
- In Vivo Molecular Electron Paramagnetic Resonance-Based Spectroscopy and Imaging of Tumor Microenvironment and Redox Using Functional Paramagnetic Probes.Antioxidants & redox signaling · 2018Review
- Continuous wave electron paramagnetic resonance of nitroxide biradicals in fluid solution.Concepts in magnetic resonance. Part A, Bridging education and research · 2018Article
- Resonators for In Vivo Imaging: Practical Experience.Applied magnetic resonance · 2017Article
- Rapid-scan EPR imaging.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2017Review
- Exchange Phenomena in the Electron Paramagnetic Resonance Spectra of the Nitroxyl and Trityl Radicals: Multifunctional Spectroscopy and Imaging of Local Chemical Microenvironment.Analytical chemistry · 2017Review
- Imaging thiol redox status in murine tumors in vivo with rapid-scan electron paramagnetic resonance.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2017Article
- Rapid Scan Electron Paramagnetic Resonance Opens New Avenues for Imaging Physiologically Important Parameters In Vivo.Journal of visualized experiments : JoVE · 2016Article
- Rapid-Scan EPR of Nitroxide Spin Labels and Semiquinones.Methods in enzymology · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
Measurement of thiol-disulfide redox status is crucial for characterization of tumor physiology. The electron paramagnetic resonance (EPR) spectra of disulfide-linked dinitroxides are readily distinguished from those of the corresponding monoradicals that are formed by cleavage of the disulfide linkage by free thiols. EPR spectra can thus be used to monitor the rate of cleavage and the thiol redox status. EPR spectra of (1)H,(14)N- and (2)H,(15)N-disulfide dinitroxides and the corresponding monoradicals resulting from cleavage by glutathione have been characterized at 250 MHz, 1.04 GHz, and 9 GHz and imaged by rapid-scan EPR at 250 MHz.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.