Evidence map›Paper›PMID 26414887›Full record

ArticleLasers in surgery and medicine2015

Detection and proportion of very early dental caries in independent living older adults.

Jennifer S Holtzman, Daniel Kohanchi, John Biren-Fetz, Margherita Fontana, Manisha Ramchandani, Kathryn Osann, Lucy Hallajian, Stephanie Mansour, Tasneem Nabelsi, Na Eun Chung and 1 more

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PubMed Full text at PMC Publisher
In one paragraph

Article in Lasers in surgery and medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Estimation of Oral Disease Burden among Older Adults in LTC: A Scoping Review.International journal of environmental research and public health · 2024
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Jennifer S HoltzmanSchool of Dentistry, University of California Los Angeles, Los Angeles, 90095, California.
Daniel KohanchiBeckman Laser Institute, University of California Irvine, Irvine, 92617, California.
John Biren-FetzBeckman Laser Institute, University of California Irvine, Irvine, 92617, California.
Margherita FontanaSchool of Dentistry, University of Michigan, Ann Arbor, 48109, Michigan.
Manisha RamchandaniSchool of Dentistry, University of California Los Angeles, Los Angeles, 90095, California.
Kathryn OsannBeckman Laser Institute, University of California Irvine, Irvine, 92617, California.
Lucy HallajianBeckman Laser Institute, University of California Irvine, Irvine, 92617, California.
Stephanie MansourBeckman Laser Institute, University of California Irvine, Irvine, 92617, California.
Tasneem NabelsiBeckman Laser Institute, University of California Irvine, Irvine, 92617, California.
Na Eun ChungBeckman Laser Institute, University of California Irvine, Irvine, 92617, California.
Petra Wilder-SmithBeckman Laser Institute, University of California Irvine, Irvine, 92617, California.
Beckman Laser Institute and Medical Clinic · USUniversity of California, Los Angeles · USUniversity of California, Irvine · USUniversity of Michigan–Ann Arbor · US

Funding

Virtual Photonocs TechnologiesP41EB015890 · NIBIB · UNIVERSITY OF CALIFORNIA-IRVINE · PI DURKIN, ANTHONY · 2012 to 2017
$7.0M
A Low-Cost Simple Oral Cancer Screening Device for Low-Resource SettingsR03EB014852 · NIBIB · UNIVERSITY OF CALIFORNIA-IRVINE · PI WILDER-SMITH, PETRA E · 2012 to 2015
$249k
NIBIB NIH HHS P41 EB015890NIBIB NIH HHS P41EB015890NIBIB NIH HHS R03 EB014852NIBIB NIH HHS R03EB014852
6 · The paper itself

Abstract

BACKGROUND AND

objectivesDental caries is an important healthcare challenge in adults over 65 years of age. Integration of oral health screening into non-dental primary care practice may improve access to preventive dental care for vulnerable populations such as the elderly. Such integration would require easy, fast, and accurate early caries detection tools. Primary goal of this study was to evaluate the diagnostic performance of optical coherence tomography (OCT) imaging for detecting very early caries in the elderly living in community-based settings. The International Caries Detection and Assessment System (ICDAS) served as gold standard. Secondary goal of this study was to provide baseline prevalence data of very early caries lesions in independent living adults aged 65+ years. MATERIALS AND

methodsSeventy-two subjects were recruited from three sites in Southern California: a retirement community, a senior health fair, and a convalescent hospital. Clinical examination was performed using the ICDAS visual criteria and this was followed by OCT imaging. The two-dimensional OCT images (B-scan) were analyzed with simple software. Locations with a log of back-scattered light intensity (BSLI) below 2.9 were scored as sound, and areas equaling or exceeding 2.9 BSLI were considered carious. Diagnostic performance of OCT imaging was compared with ICDAS score.

resultsOCT-based diagnosis demonstrated very good sensitivity (95.1%) and good specificity (85.8%). 54.7% of dentate subjects had at least one tooth with very early coronal caries.

conclusionsEarly coronal decay is prevalent in the unrestored pits and fissures of coronal surfaces of teeth in independent living adults aged 65+ years. Though OCT imaging coupled with a simple diagnostic algorithm can accurately detect areas of very early caries in community-based settings, existing devices are expensive and not well-suited for use by non-dental health care providers. Simple, inexpensive, fast, and accurate tools for early caries detection by field health care providers working in non-traditional settings are urgently needed to support inter-professional dental health management.

Indexed as

Independent LivingTomography, Optical CoherenceAgedAge FactorsCaliforniaCohort StudiesDental CariesEarly DiagnosisFemaleHumansMalePrevalenceSensitivity and Specificitycoronal cariesdental decaydiagnostic imagingICDASinter-professional health careoptical coherence tomographyoral diagnosis

Identifiers

PMID26414887
PMCPMC4699682
OpenAlexW2146488702

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.