Evidence map›Paper›PMID 26414775›Full record

ArticleArthritis care & research2016

Poverty, Depression, or Lost in Translation? Ethnic and Language Variation in Patient-Reported Outcomes in Rheumatoid Arthritis.

Patricia P Katz, Jennifer Barton, Laura Trupin, Gabriela Schmajuk, Jinoos Yazdany, Pedro J Ruiz, Edward Yelin

Open access · greenAbstract read
In one paragraph

Article in Arthritis care & research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Health Disparities in Rheumatology in the United States.Open access rheumatology : research and reviews · 2025
    Review
  4. Understanding Health Equity in Patient-Reported Outcomes.The journal of allergy and clinical immunology. In practice · 2024
    Review
  5. Article
  6. Article
  7. Managing patients using telerheumatology: Lessons from a pandemic.Best practice & research. Clinical rheumatology · 2021
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Patricia P KatzUniversity of California, San Francisco.
Jennifer BartonPortland VA Medical Center, Portland, Oregon.
Laura TrupinUniversity of California, San Francisco.
Gabriela SchmajukUniversity of California, San Francisco.
Jinoos YazdanyUniversity of California, San Francisco.
Pedro J RuizCalifornia Pacific Medical Center, San Francisco, California.
Edward YelinUniversity of California, San Francisco.
University of California, San Francisco · USCalifornia Pacific Medical Center · USPortland VA Medical Center · US

Funding

The Interplay of Sociodemographic and Genetic Factors in SLE Health DisparitiesP60AR053308 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI YELIN, EDWARD H · 2006 to 2016
$11.8M
Goal concordance in rheumatoid arthritis in diverse populationsK23AR064372 · NIAMS · OREGON HEALTH & SCIENCE UNIVERSITY · PI BARTON, JENNIFER L · 2015 to 2019
$805k
A rational approach to liver toxicity monitoring in methotrexate usersK23AR063770 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SCHMAJUK, GABRIELA · 2013 to 2017
$670k
NIAMS NIH HHS K23 AR063770NIAMS NIH HHS K23 AR064372NIAMS NIH HHS P60 AR053308
6 · The paper itself

Abstract

objectiveDespite advances in therapies, disparities in outcomes have been documented for rheumatoid arthritis (RA) patients for both ethnicity and English language proficiency. The goals of these analyses were to compare differences in RA patient-reported outcomes, by both self-identification of ethnicity and English language proficiency, and to identify factors that might explain differences among groups.

methodsData were collected through structured telephone interviews of a longitudinal cohort with physician-diagnosed RA (n = 438); only women were included (n = 335). Three groups were defined based on self-reported ethnicity and English proficiency: white/English (n = 219), Hispanic/English (n = 39), and Hispanic/Spanish (n = 77). Outcomes examined were patient-reported physical functioning, pain, and presence of moderate or severe fatigue. Multivariate regression analyses compared outcomes among groups, adjusting for sociodemographic characteristics, health and disease factors, and depression.

resultsHispanic/Spanish women had worse function, pain, and fatigue than either English-proficient group. Depression was associated with all outcomes (P < 0.0001), and accounted for greater differentials in scores than ethnicity/language proficiency. In interaction analyses, differences between women who were and were not depressed were greater for Hispanic/English than for Hispanic/Spanish. Nondepressed Hispanic/Spanish scores were significantly worse than nondepressed Hispanic/English, i.e., the impact of depression was less for Hispanic/Spanish women because both depressed and nondepressed women in this group reported worse outcomes. After adjustment for sociodemographic factors and depression, language remained significantly associated with outcomes.

conclusionDisparities in patient-reported outcomes may be driven less by ethnicity than by sociodemographic or psychological factors. Measurement instruments that are not culturally appropriate and equivalent may also hamper meaningful analyses of disparities.

Indexed as

Health Status DisparitiesPatient Reported Outcome MeasuresAdultAgedArthritis, RheumatoidCultural CharacteristicsDepressionFemaleHispanic or LatinoHumansLanguageMiddle AgedPovertyRegression AnalysisTranslationsWhite People

Identifiers

PMID26414775
PMCPMC4809778
OpenAlexW2296505315

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.