ReviewJAMA pediatrics2015
Inflammatory Bowel Disease in Children and Adolescents.
Review in JAMA pediatrics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 412 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Non Invasive Characterization of Pediatric Inflammatory Bowel Diseases Using Multispectral Optoacoustic Tomography
Personalized Exercise Coaching to Improve Quality of Life in Pediatric IBD - FIT4IBDKids: Study Protocol
Who cites it
412 citing papers in PubMed, 6 syntheses or guidelines pooled it, 747 citations in OpenAlex.
- Dual biologics or combination therapy with small molecules in pediatric inflammatory bowel disease: a systematic review and meta-analysis.World journal of pediatrics : WJP · 2026Pooled it
- Pooled it
- Caregiving Experiences of Caregivers of Adolescents With Inflammatory Bowel Disease: A Qualitative Meta-Synthesis.Nursing open · 2025Pooled it
- Assessing the therapeutic potential of rutin in alleviating symptoms of inflammatory bowel disease: a meta-analysis.Frontiers in pharmacology · 2025Pooled it
- Pooled it
- Isotretinoin Exposure and Risk of Inflammatory Bowel Disease: A Systematic Review with Meta-Analysis and Trial Sequential Analysis.American journal of clinical dermatology · 2023Pooled it
- Biofeedback-Enhanced Cognitive-Behavioral Therapy Delivered Virtually to Youth With Inflammatory Bowel Disease: A Randomized Controlled Trial.Inflammatory bowel diseases · 2025Trial
- Short-term Psychodynamic Psychotherapy in Addition to Standard Medical Therapy Increases Clinical Remission in Adolescents and Young Adults with Inflammatory Bowel Disease: a Randomised Controlled Trial.Journal of Crohn's & colitis · 2024Trial
- Gut Microbiota-Dependent Tryptophan Metabolism Drives the Therapeutic Effects of Baitouweng Tang in Colitis via the AhR Pathway.Food science & nutrition · 2026Article
- Report of Meckel Diverticulum Mimicking Stricturing Crohn's Disease in an Adolescent Boy.ACG case reports journal · 2026Article
- Sex Differences in Growth Recovery among Children with Crohn's Disease.Gut and liver · 2026Article
- Evaluation of the Correlation of Calprotectin and SES-CD Score at the Time of Diagnosis and Follow-up After Diagnosis in Pediatric Patients With Crohn's Disease in Korea.Journal of Korean medical science · 2026Article
- Article
- C-Reactive Protein-to-Albumin Ratio in Pediatric Inflammatory Bowel Disease: Associations with Disease Activity and Comparison with C-Reactive Protein Alone.Diagnostics (Basel, Switzerland) · 2026Article
- Article
- Mucin armoured diethylaminoethyl-dextran cloaked rebamipide based oral nanoformulation for the therapy of inflammatory bowel disease.Materials today. Bio · 2026Article
- Exploring endoscopy sedation experiences in young adults with pediatric-onset inflammatory bowel disease after transfer to adult gastroenterology care.Journal of the Canadian Association of Gastroenterology · 2026Article
- Risks of Undertreatment and Overtreatment in Pediatric Inflammatory Bowel Disease: Navigating the Balance.Paediatric drugs · 2026Review
- Discovery of 7-azaindole-3-acrylamide inhibitors of inflammasomes/IL-1β for the treatment of inflammatory bowel disease.Molecular diversity · 2026Article
- Prenatal Exposure to Acid-Suppressive Medications and Incident Risk of Inflammatory Bowel Disease in Children.JAMA network open · 2026Article
352 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
The inflammatory bowel diseases (IBDs), including ulcerative colitis and Crohn disease, are chronic inflammatory disorders of the gastrointestinal tract most often diagnosed in adolescence and young adulthood, with a rising incidence in pediatric populations. These disorders are common enough in children that most pediatricians and other pediatric clinicians will encounter children with IBD in their general practice. Inflammatory bowel disease is caused by a dysregulated mucosal immune response to the intestinal microflora in genetically predisposed hosts. Although children can present with the classic symptoms of weight loss, abdominal pain, and bloody diarrhea, many present with nonclassic symptoms of isolated poor growth, anemia, or other extraintestinal manifestations. Once IBD is diagnosed, the goals of therapy consist of eliminating symptoms, normalizing quality of life, restoring growth, and preventing complications while minimizing the adverse effects of medications. Unique considerations when treating children and adolescents with IBD include attention to the effects of the disease on growth and development, bone health, and psychosocial functioning. The purpose of this review is to provide a contemporary overview of the epidemiologic features, pathogenesis, diagnosis, and management of IBD in children and adolescents.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.