ReviewPopulation health management2015
Implications of Overdiagnosis: Impact on Screening Mammography Practices.
Review in Population health management, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 1 synthesis or guideline pooled it, 82 citations in OpenAlex.
- Breast cancer screening in sub-Saharan Africa: a systematic review and ethical appraisal.BMC cancer · 2022Pooled it
- Does Messaging for Reducing Breast Cancer Overscreening in Older Women Have Differential Responses among Medical Minimizers and Maximizers?Medical decision making : an international journal of the Society for Medical Decision Making · 2026Trial
- The effect of conflicting versus consistent messaging on older women's support for breast cancer screening cessation.Patient education and counseling · 2025Trial
- Effect of Messaging on Support for Breast Cancer Screening Cessation Among Older US Women: A Randomized Clinical Trial.JAMA network open · 2024Trial
- The perceived ethical appropriateness of messaging on breast cancer screening cessation among older women.Patient education and counseling · 2025Article
- Article
- Clinicopathological and Genomic Identification of Breast Cancers with No Impact on Mortality.Cancers · 2024Article
- Inappropriate requests for cranial CT scans in emergency departments increase overuse and reduce test performance.Emergency radiology · 2023Article
- Early Mammogram Screening's Impact on Early Breast Cancer Detection in Underserved Populations.Cureus · 2023Article
- Characteristics of breast cancers detected by screening mammography in Taiwan: a single institute's experience.BMC women's health · 2023Article
- History of Mammography: Analysis of Breast Imaging Diagnostic Achievements over the Last Century.Healthcare (Basel, Switzerland) · 2023Review
- Overdiagnosis Due to Screening Mammography for Breast Cancer among Women Aged 40 Years and Over: A Systematic Review and Meta-Analysis.Journal of personalized medicine · 2023Review
- Breast Cancer in Asia: Incidence, Mortality, Early Detection, Mammography Programs, and Risk-Based Screening Initiatives.Cancers · 2022Review
- Artificial intelligence in breast cancer imaging: risk stratification, lesion detection and classification, treatment planning and prognosis-a narrative review.Exploration of targeted anti-tumor therapy · 2022Review
- Advances in Analyzing the Breast Cancer Lipidome and Its Relevance to Disease Progression and Treatment.Journal of mammary gland biology and neoplasia · 2021Review
- Breast cancer risk stratification for mammographic screening: A nation-wide screening cohort of 24,431 women in Singapore.Cancer medicine · 2021Article
- Mixed-Methods Study to Predict Upstaging of DCIS to Invasive Disease on Mammography.AJR. American journal of roentgenology · 2021Article
- Multi-modal imaging of high-risk ductal carcinoma in situ of the breast using C2Am: a targeted cell death imaging agent.Breast cancer research : BCR · 2021Article
- Association between Breast Cancer Screening Intention and Behavior in the Context of Screening Cessation in Older Women.Medical decision making : an international journal of the Society for Medical Decision Making · 2021Article
- Ductal Carcinoma In Situ Biology, Language, and Active Surveillance: A Survey of Breast Radiologists' Knowledge and Opinions.Journal of the American College of Radiology : JACR · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This review article explores the issue of overdiagnosis in screening mammography. Overdiagnosis is the screen detection of a breast cancer, histologically confirmed, that might not otherwise become clinically apparent during the lifetime of the patient. While screening mammography is an imperfect tool, it remains the best tool we have to diagnose breast cancer early, before a patient is symptomatic and at a time when chances of survival and options for treatment are most favorable. In 2015, an estimated 231,840 new cases of breast cancer (excluding ductal carcinoma in situ) will be diagnosed in the United States, and some 40,290 women will die. Despite these data, screening mammography for women ages 40-69 has contributed to a substantial reduction in breast cancer mortality, and organized screening programs have led to a shift from late-stage diagnosis to early-stage detection. Current estimates of overdiagnosis in screening mammography vary widely, from 0% to upwards of 30% of diagnosed cancers. This range reflects the fact that measuring overdiagnosis is not a straightforward calculation, but usually one based on different sets of assumptions and often biased by methodological flaws. The recent development of tomosynthesis, which creates high-resolution, three-dimensional images, has increased breast cancer detection while reducing false recalls. Because the greatest harm of overdiagnosis is overtreatment, the key goal should not be less diagnosis but better treatment decision tools. (Population Health Management 2015;18:S3-S11).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.