ArticleJournal of neurotrauma2016
Cerebral Blood Flow Alterations in Acute Sport-Related Concussion.
Article in Journal of neurotrauma, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
80 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Using neuroimaging to identify sex differences in adults with sports-related concussion: a systematic review.Brain imaging and behavior · 2025Pooled it
- A Systematic Review of ASL Perfusion MRI in Mild TBI.Neuropsychology review · 2023Pooled it
- Concussion and the autonomic nervous system: An introduction to the field and the results of a systematic review.NeuroRehabilitation · 2018Pooled it
- Predictors of clinical recovery from concussion: a systematic review.British journal of sports medicine · 2017Pooled it
- The Integrated Effect of Physical Activity and Sleep Problems on Concussion Symptom Resolution.Journal of sport rehabilitation · 2026Article
- A Proposed Novel Neurovascular Mechanism for Brain Network Dysfunction After Traumatic Injury.Annals of biomedical engineering · 2026Article
- Cognitive Outcomes Following Paediatric Mild Traumatic Brain Injury: A Systematic Review and Meta-Analysis of Studies up to 2025.Neuropsychology review · 2026Review
- A One-Year Retrospective Study of the Occurrence of Sport-Related Concussions in Japanese University Sports: Characteristics of Athletes with Multiple Occurrences.Sports (Basel, Switzerland) · 2026Article
- The Role of MRI in Debunking the Fallacy of "Mild" Traumatic Brain Injury.Journal of magnetic resonance imaging : JMRI · 2026Review
- Memory outcomes and interventions after sports-related traumatic brain injuries in pediatric and young adult athletes: a scoping review.Journal of pediatric psychology · 2025Article
- Sport-Related Concussions in High School Athletes: A Comprehensive Update.Current neurology and neuroscience reports · 2025Review
- Traumatic brain injury causes early aggregation of beta-amyloid peptides and NOTCH3 reduction in vascular smooth muscle cells of leptomeningeal arteries.Acta neuropathologica · 2025Article
- Use of physical exertion to enhance objective testing following mild traumatic brain injury: a systematic review.BMJ open sport & exercise medicine · 2025Article
- Current and prospective roles of magnetic resonance imaging in mild traumatic brain injury.Brain communications · 2025Review
- Sensor-Assisted Analysis of Autonomic and Cerebrovascular Dysregulation following Concussion in an Individual with a History of Ten Concussions: A Case Study.Sensors (Basel, Switzerland) · 2024Article
- Potential Neuroprotective Role of Neurotrophin in Traumatic Brain Injury.CNS & neurological disorders drug targets · 2024Review
- Neuroimaging, wearable sensors, and blood-based biomarkers reveal hyperacute changes in the brain after sub-concussive impacts.Brain multiphysics · 2023Article
- Autonomic nervous system dysfunction in pediatric sport-related concussion: a systematic review.The Journal of the Canadian Chiropractic Association · 2023Article
- Concussion: Beyond the Cascade.Cells · 2023Review
- Mild traumatic brain injury as a pathological process.Heliyon · 2023Review
20 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Sport-related concussion (SRC) is a major health problem, affecting millions of athletes each year. While the clinical effects of SRC (e.g., symptoms and functional impairments) typically resolve within several days, increasing evidence suggests persistent neurophysiological abnormalities beyond the point of clinical recovery after injury. This study aimed to evaluate cerebral blood flow (CBF) changes in acute SRC, as measured using advanced arterial spin labeling (ASL) magnetic resonance imaging (MRI). We compared CBF maps assessed in 18 concussed football players (age, 17.8 ± 1.5 years) obtained within 24 h and at 8 days after injury with a control group of 19 matched non-concussed football players. While the control group did not show any changes in CBF between the two time-points, concussed athletes demonstrated a significant decrease in CBF at 8 days relative to within 24 h. Scores on the clinical symptom (Sport Concussion Assessment Tool 3, SCAT3) and cognitive measures (Standardized Assessment of Concussion [SAC]) demonstrated significant impairment (vs. pre-season baseline levels) at 24 h (SCAT, p < 0.0001; SAC, p < 0.01) but returned to baseline levels at 8 days. Two additional computerized neurocognitive tests, the Automated Neuropsychological Assessment Metrics and Immediate Post-Concussion and Cognitive Testing, showed a similar pattern of changes. These data support the hypothesis that physiological changes persist beyond the point of clinical recovery after SRC. Our results also indicate that advanced ASL MRI methods might be useful for detecting and tracking the longitudinal course of underlying neurophysiological recovery from concussion.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.