ArticlePloS one2015
Comparative Evaluation of the Vector Competence of Four South American Populations of the Rhipicephalus sanguineus Group for the Bacterium Ehrlichia canis, the Agent of Canine Monocytic Ehrlichiosis.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 1 of them a synthesis that pooled it.
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Who cites it
54 citing papers in PubMed, 1 synthesis or guideline pooled it, 151 citations in OpenAlex.
- Tick-borne zoonoses in the Order Rickettsiales and Legionellales in Iran: A systematic review.PLoS neglected tropical diseases · 2018Pooled it
- Species diversity and infestation patterns of ixodid ticks associated with dromedary camels (Camelus dromedarius) under arid and semi-arid conditions in Southern Algeria.Tropical animal health and production · 2026Article
- Detection of Ehrlichia canis in Rhipicephalus sanguineus and Dermacentor marginatus from sylvatic environments in Southern Italy.Veterinary research communications · 2026Article
- Canine vector-borne diseases: a changing world demands a new preventive strategy from veterinarians.Parasites & vectors · 2026Review
- Anaplasmataceae circulation in wild mammals and ticks from Goiás state, midwestern Brazil.Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria · 2026Article
- Are Babesia vogeli genotypes associated with Rhipicephalus sanguineus and Rhipicephalus linnaei distribution?Parasites & vectors · 2025Article
- Fatal coinfection with Hepatozoon canis, Babesia vogeli, Ehrlichia canis, and Bartonella clarridgeiae in a dog from Argentina.Veterinary research communications · 2025Article
- The Rhipicephalus sanguineus group: updated list of species, geographical distribution, and vector competence.Parasites & vectors · 2024Review
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- Differential susceptibility of geographically distinctEmerging microbes & infections · 2024Article
- Feline Vector-Borne Diseases and Their Possible Association with Hematological Abnormalities in Cats from Midwestern Brazil.Microorganisms · 2024Article
- American mitogenome reference for the tropical brown dog tick,Current research in parasitology & vector-borne diseases · 2024Article
- Predicting the Impact of Climate Change on the Distribution ofSustainability · 2023Article
- Geographic Distribution and Seasonality of Brown Dog Tick Lineages in the United States.Journal of medical entomology · 2023Article
- Ehrlichiosis in Dogs: A Comprehensive Review about the Pathogen and Its Vectors with Emphasis on South and East Asian Countries.Veterinary sciences · 2022Review
- Novel Ehrlichia canis genogroup in dogs with canine ehrlichiosis in Cuba.Parasites & vectors · 2022Article
- Genetic Variation inInternational journal of environmental research and public health · 2022Article
- Molecular Detection of Tick-Borne Agents in Cats from Southeastern and Northern Brazil.Pathogens (Basel, Switzerland) · 2022Article
- Article
- Occurrence of tick-borne pathogens in dogs in a coastal region of the state of Ceará, northeastern Brazil.Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria · 2022Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study compared the vector competence of four populations of Rhipicephalus sanguineus group ticks for the bacterium Ehrlichia canis, the agent of canine monocytic ehrlichiosis (CME). Ticks (larvae and nymphs) from the four populations-one from São Paulo state, southeastern Brazil (BSP), one from Rio Grande do Sul state, southern Brazil (BRS), one from Argentina (ARG), and one from Uruguay (URU)-were exposed to E. canis infection by feeding on dogs that were experimentally infected with E. canis. Engorged ticks (larvae and nymphs) were allowed to molt to nymphs and adults, respectively, which were tested by molecular analysis (E. canis-specific PCR assay) and used to infest naïve dogs. Through infestation of adult ticks on naïve dogs, after nymphal acquisition feeding on E. canis-infected dogs, only the BSP population was shown to be competent vectors of E. canis, i.e., only the dogs infested with BSP adult ticks developed clinical illness, seroconverted to E. canis, and yielded E. canis DNA by PCR. This result, demonstrated by two independent replications, is congruent with epidemiological data, since BSP ticks were derived from São Paulo state, Brazil, where CME is highly endemic. On the other hand, BRS, ARG, and URU ticks were derived from a geographical region (South America southern cone) where CME has never been properly documented. Molecular analysis of unfed adults at 30 days post molting support these transmission results, since none of the BRS, ARG, and URU ticks were PCR positive, whereas 1% of the BSP nymphs and 31.8% of the BSP adults contained E. canis DNA. We conclude that the absence or scarcity of cases of CME due to E. canis in the South America southern cone is a result of vector incompetence of the R. sanguineus group ticks that prevail on dogs in this part of South America.
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