ReviewCurrent opinion in endocrinology, diabetes, and obesity2015
Bone loss in HIV: a contemporary review.
Review in Current opinion in endocrinology, diabetes, and obesity, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 1 synthesis or guideline pooled it, 67 citations in OpenAlex.
- Bone fracture among people living with HIV: A systematic review and meta-regression of prevalence, incidence, and risk factors.PloS one · 2020Pooled it
- Vitamin D and Calcium Supplement Attenuate Bone Loss among HIVInfected Patients Receiving Tenofovir Disoproxil Fumarate/Emtricitabine/ Efavirenz: An Open-Label, Randomized Controlled Trial.Current HIV research · 2020Trial
- Effects of Vitamin D Supplementation on Bone Mineral Density and Bone Markers in HIV-Infected Youth.Journal of acquired immune deficiency syndromes (1999) · 2017Trial
- The Influence of Exercise on Cardiovascular Health in Sedentary Adults With Human Immunodeficiency Virus.The Journal of cardiovascular nursingTrial
- Relationships Between Physical Activity and Bone Density in People Living with HIV: Results from the SATURN-HIV Study.The Journal of the Association of Nurses in AIDS Care : JANACTrial
- Multimodal Bone Fragility Profiling in People Living with HIV: Trabecular Bone Score, Calcaneal Quantitative Ultrasound, and Sarcopenia Screening.Medicina (Kaunas, Lithuania) · 2026Article
- The State of the Science on Chronic Comorbidities and Aging in Children and Adolescents with perinatally-acquired HIV.Current HIV/AIDS reports · 2025Review
- Bone Mineral Density in HIV-Infected People-the Experience of Craiova Regional Center.Biomedicines · 2025Article
- Narrative Review on the Management of Neck of Femur Fractures in People Living with HIV: Challenges, Complications, and Long-Term Outcomes.Microorganisms · 2025Review
- Article
- Multivariable analysis of bone mass reduction risk prediction and anxiety status in male HIV/AIDS patients.Frontiers in reproductive health · 2025Article
- Bone Tissue Changes in Individuals Living with HIV/AIDS: The Importance of a Hierarchical Approach in Investigating Bone Fragility.Journal of personalized medicine · 2024Review
- Unilateral avascular necrosis of the right hip in an HIV patient with tearing of the rectus femoris and adductor longus muscles.BMJ case reports · 2024Article
- Postmenopausal women with HIV have increased tooth loss.BMC oral health · 2024Article
- Biochemical Markers of Calcium and Bone Metabolism during and after Lactation in Ugandan Women with HIV on Universal Maternal Antiretroviral Therapy.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2023Article
- Factors Informing the Development of a Clinical Pathway and Patients' Quality of Life after a Non-Union Fracture of the Lower Limb.Healthcare (Basel, Switzerland) · 2023Article
- Review
- Reviewing the Potential Links between Viral Infections and TDP-43 Proteinopathies.International journal of molecular sciences · 2023Review
- The evaluation of risk factors related to reduced bone mineral density in young people living with HIV.African health sciences · 2022Article
- Cross-sectional comparison of age- and gender-related comorbidities in people living with HIV in Canada.Medicine · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
Abstract
purpose of reviewBecause of antiretroviral therapy (ART), people are living with HIV infection longer than ever before. As this patient group ages, it is expected that medical comorbidities such as osteoporosis and fragility fractures will increase. The purpose of this review is to address the epidemiology and what is known regarding the pathogenesis of bone loss in people living with HIV infection with a focus on recently published literature. RECENT
findingsHIV-infected individuals are at increased risk for low bone mineral density and bone fractures. The cause of bone loss in HIV is multifactorial including traditional risk factors some of which disproportionately affect HIV-infected individuals and alterations in bone metabolism due to ART, HIV viral proteins and chronic inflammation. Lifestyle modification, changing ART, calcium and vitamin D supplementation and pharmacologic treatment for osteoporosis may all be employed to abrogate bone loss in this patient group. SUMMARY: Clinicians should be aware of the contributors to bone loss in people living with HIV in order to recognize high-risk individuals and to take appropriate steps to address modifiable risk factors to prevent future fracture.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.