ArticleJournal of the American Chemical Society2015
A Fluorinated Ligand Enables Room-Temperature and Regioselective Pd-Catalyzed Fluorination of Aryl Triflates and Bromides.
Article in Journal of the American Chemical Society, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 128 citations in OpenAlex.
- Direct Regioselective para-Fluorination via I(I)/I(III) Catalysis.Angewandte Chemie (International ed. in English) · 2026Article
- Fluorinated terpenoids and their fluorine-containing derivatives.RSC advances · 2026Review
- Reaction-conditioned generative model for catalyst design and optimization with CatDRX.Communications chemistry · 2025Article
- IPr*Chemistry (Weinheim an der Bergstrasse, Germany) · 2024Article
- Late-stage modification of bioactive compounds: Improving druggability through efficient molecular editing.Acta pharmaceutica Sinica. B · 2024Review
- Synthesis and Photolysis Properties of a New Chloroquine Photoaffinity Probe.Molecules (Basel, Switzerland) · 2024Article
- Unveiling the Latent Reactivity of Cp* Ligands (CInorganic chemistry · 2023Article
- Studying Regioisomer Formation in the Pd-Catalyzed Fluorination of Cyclic Vinyl Triflates: Evidence for in situ Ligand Modification.Angewandte Chemie (International ed. in English) · 2023Article
- Abiotic peptides as carriers of information for the encoding of small-molecule library synthesis.Science (New York, N.Y.) · 2023Article
- Stereoselective [2+2]-Cycloadditions of chiral allenic ketones and alkenes: Applications towards the synthesis of benzocyclobutenes and endiandric acids.Tetrahedron · 2022Article
- Mechanistic study of the bismuth mediated fluorination of arylboronic esters and further rational design.RSC advances · 2022Article
- Mechanism of the Aryl-F Bond-Forming Step from Bi(V) Fluorides.Journal of the American Chemical Society · 2022Article
- A Neophyl Palladacycle as an Air- and Thermally Stable Precursor to Oxidative Addition Complexes.Organic letters · 2021Article
- Article
- Mechanochemistry allows carrying out sensitive organometallic reactions in air: glove-box-and-Schlenk-line-free synthesis of oxidative addition complexes from aryl halides and palladium(0).Chemical science · 2019Article
- Base-Promoted, Remote C-H Activation at a Cationic (ηJournal of the American Chemical Society · 2019Article
- Recent advances in transition-metal-catalyzed incorporation of fluorine-containing groups.Beilstein journal of organic chemistry · 2019Review
- Ylide-Functionalized Phosphines: Strong Donor Ligands for Homogeneous Catalysis.Angewandte Chemie (International ed. in English) · 2018Article
- Breaking the Base Barrier: An Electron-Deficient Palladium Catalyst Enables the Use of a Common Soluble Base in C-N Coupling.Journal of the American Chemical Society · 2018Article
- Metal-Mediated Halogen Exchange in Aryl and Vinyl Halides: A Review.Frontiers in chemistry · 2018Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
A new biaryl monophosphine ligand (AlPhos, L1) allows for the room-temperature Pd-catalyzed fluorination of a variety of activated (hetero)aryl triflates. Furthermore, aryl triflates and bromides that are prone to give mixtures of regioisomeric aryl fluorides with Pd-catalysis can now be converted to the desired aryl fluorides with high regioselectivity. Analysis of the solid-state structures of several Pd(II) complexes, as well as density functional theory (DFT) calculations, shed light on the origin of the enhanced reactivity observed with L1.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.