Evidence map›Paper›PMID 26413847›Full record

ArticleJournal of acquired immune deficiency syndromes (1999)2016

Brief Report: Prevalence of Latent Rheumatic Heart Disease Among HIV-Infected Children in Kampala, Uganda.

Brigette Gleason, Grace Mirembe, Judith Namuyonga, Emmy Okello, Peter Lwabi, Irene Lubega, Sulaiman Lubega, Victor Musiime, Cissy Kityo, Robert A Salata and 1 more

Abstract read
In one paragraph

Article in Journal of acquired immune deficiency syndromes (1999), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Stroke in HIV.The Canadian journal of cardiology · 2019
    Review
  9. Observational
  10. Review
  11. Rheumatic Heart Disease Treatment Cascade in Uganda.Circulation. Cardiovascular quality and outcomes · 2017
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Brigette Gleason*Case Western Reserve University School of Medicine, Cleveland, OH; †University Hospitals Case Medical Center, Cleveland, OH; ‡Joint Clinical Research Center, Kampala, Uganda; §Makerere University School of Medicine, Kampala, Uganda; and ‖Uganda Heart Institute, Kampala, Uganda.
Grace Mirembe
Judith Namuyonga
Emmy Okello
Peter Lwabi
Irene Lubega
Sulaiman Lubega
Victor Musiime
Cissy Kityo
Robert A Salata
Chris T Longenecker
Makerere University · UGJoint Clinical Research Centre · UGUniversity School · USUganda Management Institute · UGUniversity Hospitals Case Medical Center · US

Funding

Linked; Building Capacity for Cardiovascular Research and Training in UgandaR24TW008861 · FIC · MAKERERE UNIVERSITY COLLEGE OF HEALTH SCIENCES · PI SEWANKAMBO, NELSON K · 2010 to 2014
$2.5M
Pericardial fat, inflammation, and structural heart disease in HIVK23HL123341 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI LONGENECKER, CHRIS TODD · 2014 to 2018
$885k
FIC NIH HHS R24 TW008861NHLBI NIH HHS K23 HL123341
6 · The paper itself

Abstract

Rheumatic heart disease (RHD) remains highly prevalent in resource-constrained settings around the world, including countries with high rates of HIV/AIDS. Although both are immune-mediated diseases, it is unknown whether HIV modifies the risk or progression of RHD. We performed screening echocardiography to determine the prevalence of latent RHD in 488 HIV-infected children aged 5-18 in Kampala, Uganda. The overall prevalence of borderline/definite RHD was 0.82% (95% confidence interval: 0.26% to 2.23%), which is lower than the published prevalence rates of 1.5%-4% among Ugandan children. There may be protective factors that decrease the risk of RHD in HIV-infected children.

Indexed as

AdolescentChildCross-Sectional StudiesDisease ProgressionEchocardiographyFemaleHIV InfectionsHumansMalePrevalenceRheumatic Heart DiseaseUganda

Identifiers

PMID26413847
PMCPMC4712089
OpenAlexW2416911455

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.