Evidence map›Paper›PMID 26413718›Full record

SynthesisPloS one2015

The Effect of Post-Exercise Cryotherapy on Recovery Characteristics: A Systematic Review and Meta-Analysis.

Erich Hohenauer, Jan Taeymans, Jean-Pierre Baeyens, Peter Clarys, Ron Clijsen

2 registry-linked trialsOpen access · goldAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 82 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
82citing papers in PubMed, 9 pooled it
12.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03885791 nacompletednot on this mapstarted 2019, after this paper: background citation

Randomized Controlled Trial of Vaginal Cryotherapy for Pelvic Floor Myofascial Pain

TypeinterventionalSponsorWashington University School of MedicineRan2019 to 2024Enrolled165ConditionsPelvic Floor Myofascial Pain, Pelvic Pain, Myofascial PainArmsvaginal cryotherapy
NCT06813690 nacompletednot on this mapstarted 2025, after this paper: background citation

Effects of Immediate and Delayed Repeated Cold Exposure After Physical Exertion: a Randomised Controlled Trial

TypeinterventionalSponsorUniversity of Applied Sciences and Arts of Southern SwitzerlandRan2025 to 2025Enrolled48ConditionsDelayed Onset Muscle Soreness (DOMS), Inflammation, Muscle Pain, Muscle DamageArmsCold Therapy with Axanova Cold Hot Pearls Maxi Pack
3 · Its place in the literature

Who cites it

82 citing papers in PubMed, 9 syntheses or guidelines pooled it, 183 citations in OpenAlex.

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  18. Acute Local Cooling to the Lower Body during Recovery Does Not Improve Repeated Vertical Jump Performance.International journal of environmental research and public health · 2021
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22 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Erich HohenauerDepartment of Business Economics, Health and Social Care, University of Applied Sciences and Arts of Southern Switzerland, Landquart / Manno, Switzerland; University College Physiotherapy Thim van der Laan, Landquart (GR), Switzerland.
Jan TaeymansHealth Department, Bern University of Applied Sciences, Berne, Switzerland; Faculty of Physical Education and Physiotherapy, Vrije Universiteit Brussel, Brussels, Belgium; Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium.
Jean-Pierre BaeyensFaculty of Physical Education and Physiotherapy, Vrije Universiteit Brussel, Brussels, Belgium; University College Physiotherapy Thim van der Laan, Landquart (GR), Switzerland; Faculty of Applied Engineering, University of Antwerp, Antwerp, Belgium.
Peter ClarysFaculty of Physical Education and Physiotherapy, Vrije Universiteit Brussel, Brussels, Belgium.
Ron ClijsenDepartment of Business Economics, Health and Social Care, University of Applied Sciences and Arts of Southern Switzerland, Landquart / Manno, Switzerland; Faculty of Physical Education and Physiotherapy, Vrije Universiteit Brussel, Brussels, Belgium; University College Physiotherapy Thim van der Laan, Landquart (GR), Switzerland.
THIM van der Laan University College Physiotherapy · CHVrije Universiteit Brussel · BEUniversity of Applied Sciences and Arts of Southern Switzerland · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this review and meta-analysis was to critically determine the possible effects of different cooling applications, compared to non-cooling, passive post-exercise strategies, on recovery characteristics after various, exhaustive exercise protocols up to 96 hours (hrs). A total of n = 36 articles were processed in this study. To establish the research question, the PICO-model, according to the PRISMA guidelines was used. The Cochrane's risk of bias tool, which was used for the quality assessment, demonstrated a high risk of performance bias and detection bias. Meta-analyses of subjective characteristics, such as delayed-onset muscle soreness (DOMS) and ratings of perceived exertion (RPE) and objective characteristics like blood plasma markers and blood plasma cytokines, were performed. Pooled data from 27 articles revealed, that cooling and especially cold water immersions affected the symptoms of DOMS significantly, compared to the control conditions after 24 hrs recovery, with a standardized mean difference (Hedges' g) of -0.75 with a 95% confidence interval (CI) of -1.20 to -0.30. This effect remained significant after 48 hrs (Hedges' g: -0.73, 95% CI: -1.20 to -0.26) and 96 hrs (Hedges' g: -0.71, 95% CI: -1.10 to -0.33). A significant difference in lowering the symptoms of RPE could only be observed after 24 hrs of recovery, favouring cooling compared to the control conditions (Hedges' g: -0.95, 95% CI: -1.89 to -0.00). There was no evidence, that cooling affects any objective recovery variable in a significant way during a 96 hrs recovery period.

Indexed as

CryotherapyExerciseC-Reactive ProteinHumansInterleukin-6Lactic AcidMyalgiaPhysical ExertionC-Reactive ProteinInterleukin-6Lactic Acid

Identifiers

PMID26413718
PMCPMC4586380
OpenAlexW2133153616

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.