Evidence map›Paper›PMID 26413536›Full record

ArticleBioMed research international2015

Soluble and Endogenous Secretory Receptors for Advanced Glycation End Products in Threatened Preterm Labor and Preterm Premature Rupture of Fetal Membranes.

Rafał Rzepka, Barbara Dołegowska, Aleksandra Rajewska, Sebastian Kwiatkowski, Daria Sałata, Marta Budkowska, Leszek Domański, Wioletta Mikołajek-Bedner, Andrzej Torbé

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Trial
  2. Review
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  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Rafał RzepkaDepartment of Obstetrics and Gynecology, Pomeranian Medical University, 70-204 Szczecin, Poland.
Barbara DołegowskaDepartment of Laboratory Diagnostics and Molecular Medicine, Pomeranian Medical University, 70-204 Szczecin, Poland.
Aleksandra RajewskaDepartment of Obstetrics and Gynecology, Pomeranian Medical University, 70-204 Szczecin, Poland.
Sebastian KwiatkowskiDepartment of Obstetrics and Gynecology, Pomeranian Medical University, 70-204 Szczecin, Poland.
Daria SałataDepartment of Laboratory Diagnostics and Molecular Medicine, Pomeranian Medical University, 70-204 Szczecin, Poland.
Marta BudkowskaDepartment of Laboratory Diagnostics and Molecular Medicine, Pomeranian Medical University, 70-204 Szczecin, Poland.
Leszek DomańskiDepartment of Nephrology, Transplantology and Internal Medicine, Pomeranian Medical University, 70-204 Szczecin, Poland.
Wioletta Mikołajek-BednerDepartment of Obstetrics and Gynecology, Pomeranian Medical University, 70-204 Szczecin, Poland.
Andrzej TorbéDepartment of Obstetrics and Gynecology, Pomeranian Medical University, 70-204 Szczecin, Poland.
Pomeranian Medical University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of the study was to compare sRAGE and esRAGE plasma levels in pregnant women with (A) threatened premature labor (n = 41), (B) preterm premature rupture of membranes (n = 49), and (C) preterm rupture of membranes at term (n = 48). The relationship between these and classic intrauterine infection markers and the latent time from symptoms up to delivery depending on RAGE's concentration were investigated. In groups A and B, a positive correlation was found between plasma sRAGE and latent time (r = 0,422; p = 0,001; r = 0,413, p = 0,004, resp.). High prognostic values were found in both groups for plasma sRAGE concentration and the latent time from symptoms up to delivery. Groups B and C presented higher levels of esRAGE than group A (526,315 ± 129,453 pg/mL and 576,212 ± 136,237 pg/mL versus 485,918 ± 133,127 pg/mL, p< 0,05). The conclusion is that sRAGE concentration can be a favorable prognostic factor in the presence of symptoms of threatened premature labor. Higher esRAGE plasma level in case of the rupture of membranes in mature and premature pregnancy suggests its participation in fetal membranes destruction.

Indexed as

AdultCase-Control StudiesFemaleHumansObstetric Labor, PrematurePregnancyPremature Rupture of Fetal MembranesReceptor for Advanced Glycation End ProductsSensitivity and SpecificityYoung AdultAGER protein, humanReceptor for Advanced Glycation End Products

Identifiers

PMID26413536
PMCPMC4564602
OpenAlexW2128927753

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.