Evidence map›Paper›PMID 26413523›Full record

ArticleBioMed research international2015

Transarterial Embolization for Hepatocellular Carcinoma: A Comparison between Nonspherical PVA and Microspheres.

Leandro Armani Scaffaro, Cleber Dario Pinto Kruel, Steffan Frosi Stella, Gabriela Leal Gravina, Geraldo Machado Filho, Carlos Podalirio Borges de Almeida, Luiz Cezar Pontes Fonseca Pinto, Mario Reis Alvares-da-Silva, Cleber Rosito Pinto Kruel

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Leandro Armani ScaffaroRadiology Division, Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, RS, Brazil.
Cleber Dario Pinto KruelSurgery Division, Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, RS, Brazil.
Steffan Frosi StellaInstitute for Health Technology Assessment, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil.
Gabriela Leal GravinaSchool of Medicine, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil.
Geraldo Machado FilhoSchool of Medicine, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil.
Carlos Podalirio Borges de AlmeidaSchool of Medicine, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil.
Luiz Cezar Pontes Fonseca PintoSchool of Medicine, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil.
Mario Reis Alvares-da-SilvaGastroenterology Division, Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, RS, Brazil.
Cleber Rosito Pinto KruelSurgery Division, Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, RS, Brazil.
Universidade Federal do Rio Grande do Sul · BRHospital de Clínicas de Porto Alegre · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transarterial chemoembolization (TACE) and transarterial embolization (TAE) have improved the survival rates of patients with unresectable hepatocellular carcinoma (HCC); however, the optimal TACE/TAE embolic agent has not yet been identified. The aim of this study was to compare the effect of two different embolic agents such as microspheres (ME) and polyvinyl alcohol (PVA) on survival, tumor response, and complications in patients with HCC submitted to transarterial embolization (TAE). Eighty HCC patients who underwent TAE between June 2008 and December 2012 at a single center were retrospectively studied. A total of 48 and 32 patients were treated with PVA and ME, respectively. There were no significant differences in survival (P = 0.679) or tumoral response (P = 0.369) between groups (PVA or ME). Overall survival rates at 12, 18, 24, 36, and 48 months were 97.9, 88.8, 78.9, 53.4, and 21.4% in the PVA-TAE group and 100, 92.9, 76.6, 58.8, and 58% in the ME-TAE group (P = 0.734). Patients submitted to TAE with ME presented postembolization syndrome more frequently when compared with the PVA group (P = 0.02). According to our cohort, the choice of ME or PVA as embolizing agent had no significant impact on overall survival.

Indexed as

MicrospheresAgedCarcinoma, HepatocellularChemoembolization, TherapeuticFemaleHumansKaplan-Meier EstimateLiver NeoplasmsMaleMiddle AgedPolyvinyl AlcoholRetrospective StudiesPolyvinyl Alcohol

Identifiers

PMID26413523
PMCPMC4564629
OpenAlexW1606190216

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.