Evidence map›Paper›PMID 26413195›Full record

ArticleInfant, child & adolescent nutrition2014

Urinary Hypoxanthine as a Measure of Increased ATP Utilization in Late Preterm Infants.

Megan S Holden, Andrew Hopper, Laurel Slater, Yayesh Asmerom, Ijeoma Esiaba, Danilo S Boskovic, Danilyn M Angeles

Open access · bronzeAbstract read
In one paragraph

Article in Infant, child & adolescent nutrition, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact, top 83% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Megan S HoldenDepartments of Basic Sciences (MSH, LS, YA, DSB, DA) and Pediatrics (AH), Loma Linda University School of Medicine; Department of Earth and Biological Sciences, Loma Linda University School of Public Health (IE), Loma Linda, California.
Andrew HopperDepartments of Basic Sciences (MSH, LS, YA, DSB, DA) and Pediatrics (AH), Loma Linda University School of Medicine; Department of Earth and Biological Sciences, Loma Linda University School of Public Health (IE), Loma Linda, California.
Laurel SlaterDepartments of Basic Sciences (MSH, LS, YA, DSB, DA) and Pediatrics (AH), Loma Linda University School of Medicine; Department of Earth and Biological Sciences, Loma Linda University School of Public Health (IE), Loma Linda, California.
Yayesh AsmeromDepartments of Basic Sciences (MSH, LS, YA, DSB, DA) and Pediatrics (AH), Loma Linda University School of Medicine; Department of Earth and Biological Sciences, Loma Linda University School of Public Health (IE), Loma Linda, California.
Ijeoma EsiabaDepartments of Basic Sciences (MSH, LS, YA, DSB, DA) and Pediatrics (AH), Loma Linda University School of Medicine; Department of Earth and Biological Sciences, Loma Linda University School of Public Health (IE), Loma Linda, California.
Danilo S BoskovicDepartments of Basic Sciences (MSH, LS, YA, DSB, DA) and Pediatrics (AH), Loma Linda University School of Medicine; Department of Earth and Biological Sciences, Loma Linda University School of Public Health (IE), Loma Linda, California.
Danilyn M AngelesDepartments of Basic Sciences (MSH, LS, YA, DSB, DA) and Pediatrics (AH), Loma Linda University School of Medicine; Department of Earth and Biological Sciences, Loma Linda University School of Public Health (IE), Loma Linda, California.
Loma Linda University · US

Funding

Procedural Pain and Hypoxia in Preterm NeonatesR21NR010407 · NINR · LOMA LINDA UNIVERSITY · PI ANGELES, DANILYN MAG-AKAT · 2007 to 2008
$437k
NINR NIH HHS R21 NR010407
6 · The paper itself

Abstract

objectiveTo examine the effect of neonatal morbidity on ATP breakdown in late preterm infants. STUDY

designUrinary hypoxanthine concentration, a marker of ATP breakdown, was measured from 82 late preterm infants on days of life (DOL) 3 to 6 using high-performance liquid chromatography. Infants were grouped according to the following diagnoses: poor nippling alone (n = 8), poor nippling plus hyperbilirubinemia (n = 21), poor nippling plus early respiratory disease (n = 26), and respiratory disease alone (n = 27).

resultsNeonates with respiratory disease alone had significantly higher urinary hypoxanthine over DOL 3 to 6 when compared with neonates with poor nippling (

conclusionsThese findings suggest that respiratory disorders significantly increase ATP degradation in late premature infants.

Indexed as

ATPhigh-performance liquid chromatographyhypoxanthinelate pretermurine

Identifiers

PMID26413195
PMCPMC4581456
OpenAlexW2099526464

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.