Evidence map›Paper›PMID 26413155›Full record

ReviewBiotechnology for biofuels2015

Advancing understanding of microbial bioenergy conversion processes by activity-based protein profiling.

Yun Liu, James K Fredrickson, Natalie C Sadler, Premchendar Nandhikonda, Richard D Smith, Aaron T Wright

Abstract readReview
In one paragraph

Review in Biotechnology for biofuels, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yun LiuBeijing Key Laboratory of Bioprocess, College of Life Science and Technology, Beijing University of Chemical Technology, 100029 Beijing, China.
James K FredricksonBiological Sciences Division, Pacific Northwest National Laboratory, 902 Battelle Blvd, MSIN J4-02, Box 999, Richland, WA 99352 USA.
Natalie C SadlerBiological Sciences Division, Pacific Northwest National Laboratory, 902 Battelle Blvd, MSIN J4-02, Box 999, Richland, WA 99352 USA.
Premchendar NandhikondaBiological Sciences Division, Pacific Northwest National Laboratory, 902 Battelle Blvd, MSIN J4-02, Box 999, Richland, WA 99352 USA.
Richard D SmithBiological Sciences Division, Pacific Northwest National Laboratory, 902 Battelle Blvd, MSIN J4-02, Box 999, Richland, WA 99352 USA.
Aaron T WrightBiological Sciences Division, Pacific Northwest National Laboratory, 902 Battelle Blvd, MSIN J4-02, Box 999, Richland, WA 99352 USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of renewable biofuels is a global priority, but success will require novel technologies that greatly improve our understanding of microbial systems biology. An approach with great promise in enabling functional characterization of microbes is activity-based protein profiling (ABPP), which employs chemical probes to directly measure enzyme function in discrete enzyme classes in vivo and/or in vitro, thereby facilitating the rapid discovery of new biocatalysts and enabling much improved biofuel production platforms. We review general design strategies in ABPP, and highlight recent advances that are or could be pivotal to biofuels processes including applications of ABPP to cellulosic bioethanol, biodiesel, and phototrophic production of hydrocarbons. We also examine the key challenges and opportunities of ABPP in renewable biofuels research. The integration of ABPP with molecular and systems biology approaches will shed new insight on the catalytic and regulatory mechanisms of functional enzymes and their synergistic effects in the field of biofuels production.

Indexed as

Activity-based protein profiling (ABPP)BiodieselCellulosic bioethanolProtein redoxProteomics

Identifiers

PMID26413155
PMCPMC4582708

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.