Evidence map›Paper›PMID 26413106›Full record

ArticleKorean circulation journal2015

Apelin Levels In Isolated Coronary Artery Ectasia.

Mehmet Zihni Bilik, İbrahim Kaplan, Abdulkadir Yıldız, Mehmet Ata Akıl, Halit Acet, Murat Yüksel, Nihat Polat, Mesut Aydın, Mustafa Oylumlu, Faruk Ertaș and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Korean circulation journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Mehmet Zihni BilikDepartment of Cardiology, Medicine Faculty, Dicle University, Diyarbakır, Turkey.
İbrahim KaplanDepartment of Biochemistry, Medicine Faculty, Dicle University, Diyarbakır, Turkey.
Abdulkadir YıldızDepartment of Cardiology, Medicine Faculty, Dicle University, Diyarbakır, Turkey.
Mehmet Ata AkılDepartment of Cardiology, Medicine Faculty, Dicle University, Diyarbakır, Turkey.
Halit AcetDepartment of Cardiology, Medicine Faculty, Dicle University, Diyarbakır, Turkey.
Murat YükselDepartment of Cardiology, Medicine Faculty, Dicle University, Diyarbakır, Turkey.
Nihat PolatDepartment of Cardiology, Medicine Faculty, Dicle University, Diyarbakır, Turkey.
Mesut AydınDepartment of Cardiology, Medicine Faculty, Dicle University, Diyarbakır, Turkey.
Mustafa OylumluDepartment of Cardiology, Medicine Faculty, Dicle University, Diyarbakır, Turkey.
Faruk ErtașDepartment of Cardiology, Medicine Faculty, Dicle University, Diyarbakır, Turkey.
Hasan KayaDepartment of Cardiology, Medicine Faculty, Dicle University, Diyarbakır, Turkey.
Sait AlanDepartment of Cardiology, Medicine Faculty, Dicle University, Diyarbakır, Turkey.
Dicle University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesThe etiopathogenesis of coronary artery ectasia (CAE) is not known completely. In most of the cases, CAE is associated with atherosclerosis; however, isolated CAE has a nonatherosclerotic mechanism. The association between atherosclerotic coronary artery disease and apelin has been examined in previous studies. However, the role of plasma apelin in isolated coronary artery ectasia has not been studied. In this study, we investigated the relationship between plasma apelin levels and isolated coronary artery ectasia. SUBJECTS AND

methodsThe study population included a total of 54 patients. Twenty-six patients had isolated CAE (53.6±8.1 years); 28 patients with normal coronary arteries (51.6±8.8 years) and with similar risk factors and demographic characteristics served as the control group. Apelin levels were measured using an enzyme-linked immunoassay kit.

resultsApelin level in the CAE group was significantly lower (apelin=0.181±0.159 ng/mL) than that in the control group (apelin=0.646±0.578 ng/mL) (p=0.033). Glucose, creatinine, total cholesterol, triglyceride, low density lipoprotein cholesterol, and high density lipoprotein cholesterol levels were not significantly different between the two groups.

conclusionIn this study, we showed that patients with isolated CAE have decreased plasma apelin levels compared with the control group. Based on the data, a relationship between plasma apelin and isolated CAE was determined.

Indexed as

Apelin protein, humanCoronary artery diseaseDilatation, pathologicInflammation

Identifiers

PMID26413106
PMCPMC4580697
OpenAlexW1913974721

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.