ReviewKorean circulation journal2015
Genetic Syndromes associated with Congenital Heart Disease.
Review in Korean circulation journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it, 89 citations in OpenAlex.
- The Association Between Congenital Heart Disease and Autism Spectrum Disorder: A Systematic Review and Meta-Analysis.Pediatric cardiology · 2023Pooled it
- Article
- Prevalence, Clinical Profile, and Factors Associated With Congenital Heart Disease in Children Diagnosed at National Referral Hospital, Bhutan: A Cross-Sectional Study.Health science reports · 2026Article
- Patterns, survival, and mortality predictors in children with down syndrome and congenital heart disease in resource-limited settings: a follow-up study.BMC pediatrics · 2026Article
- Incidence and Factors Associated with Neurological Complications Following Pediatric Heart Surgery: A Retrospective Study.Journal of clinical medicine · 2026Article
- Significant Congenital Cardiovascular Malformations and Falling Birth Rates: The Nevada Experience.Pediatric cardiology · 2026Article
- Genetic Syndromes and Multimorbidity in Adults with Congenital Heart Disease and Heart Failure: Insights from the PATHFINDER-CHD Registry.Journal of clinical medicine · 2026Article
- Phenotypic profile and predictors of adverse outcomes during paediatric cardiac catheterisation at an academic hospital, South Africa.Frontiers in pediatrics · 2026Article
- Clinical and Genotypic Insights into Turner Syndrome: Emphasis on Cardiovascular Abnormalities.Journal of the ASEAN Federation of Endocrine Societies · 2025Article
- Evaluation of prenatal and postnatal outcomes of fetuses with intrauterine cardiac anomalies: Tertiary center experience.Turkish journal of obstetrics and gynecology · 2025Article
- Cognitive Outcomes and Delirium After Cardiac Neurodevelopmental Program Implementation for Children With Congenital Heart Disease.JAMA network open · 2025Article
- Paternal peri-conceptional physical activity and the risk of congenital heart disease in offspring: A case-control study.Andrology · 2025Observational
- 2q31 microdeletion syndrome with the velocardiofacial phenotype and review of the literature: a case report.BMC pediatrics · 2024Review
- Article
- Outcomes and Associated Extracardiac Malformations in Neonates from Colombia with Severe Congenital Heart Disease.Pediatric cardiology · 2024Article
- Analysis of Down syndrome newborn outcomes in three neonatal intensive care units in Rio de Janeiro, Brazil.Revista da Associacao Medica Brasileira (1992) · 2024Article
- Endocrine Disorders in a Newborn with Heterozygous Galactosemia, Down Syndrome and Complex Cardiac Malformation: Case Report.Medicina (Kaunas, Lithuania) · 2023Article
- Genetic Defects in Children with Cardiac Anomalies/Malformations: Noonan and CFC Syndromes.Journal of pediatric genetics · 2023Article
- Population Prevalence, Cancer Risk, and Mortality Risk of Turner Syndrome in South Korean Women Based on National Health Insurance Service Data.Yonsei medical journal · 2022Article
- Prevalence of Genetic Diagnoses in a Cohort With Valvar Pulmonary Stenosis.Circulation. Genomic and precision medicine · 2022Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recent research has demonstrated that genetic alterations or variations contribute considerably to the development of congenital heart disease. Many kinds of genetic tests are commercially available, and more are currently under development. Congenital heart disease is frequently accompanied by genetic syndromes showing both cardiac and extra-cardiac anomalies. Congenital heart disease is the leading cause of birth defects, and is an important cause of morbidity and mortality during infancy and childhood. This review introduces common genetic syndromes showing various types of congenital heart disease, including Down syndrome, Turner syndrome, 22q11 deletion syndrome, Williams syndrome, and Noonan syndrome. Although surgical techniques and perioperative care have improved substantially, patients with genetic syndromes may be at an increased risk of death or major complications associated with surgery. Therefore, risk management based on an accurate genetic diagnosis is necessary in order to effectively plan the surgical and medical management and follow-up for these patients. In addition, multidisciplinary approaches and care for the combined extra-cardiac anomalies may help to reduce mortality and morbidity accompanied with congenital heart disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.