Evidence map›Paper›PMID 26413085›Full record

ArticleThe journal of venomous animals and toxins including tropical diseases2015

Snake venom galactoside-binding lectins: a structural and functional overview.

Marco A Sartim, Suely V Sampaio

Abstract read
In one paragraph

Article in The journal of venomous animals and toxins including tropical diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Toxins · 2023
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Neutrophils activated by BJcuL, a C-type lectin isolated fromThe journal of venomous animals and toxins including tropical diseases · 2020
    Article
  16. Subproteome ofThe journal of venomous animals and toxins including tropical diseases · 2019
    Article
  17. Article
  18. Review
  19. Cytotoxic activity ofThe journal of venomous animals and toxins including tropical diseases · 2016
    Article
  20. Experimental Lachesis muta rhombeata envenomation and effects of soursop (Annona muricata) as natural antivenom.The journal of venomous animals and toxins including tropical diseases · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Marco A SartimDepartamento de Análises Clínicas, Toxicológicas e Bromatológicas, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo (USP), Avenida do Café, s/n, Ribeirão Preto, SP CEP 14040-903 Brazil.
Suely V SampaioDepartamento de Análises Clínicas, Toxicológicas e Bromatológicas, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo (USP), Avenida do Café, s/n, Ribeirão Preto, SP CEP 14040-903 Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Snake venom galactoside-binding lectins (SVgalLs) comprise a class of toxins capable of recognizing and interacting with terminal galactoside residues of glycans. In the past 35 years, since the first report on the purification of thrombolectin from Bothrops atrox snake venom, several SVgalLs from Viperidae and Elapidae snake families have been described, as has progressive improvement in the investigation of structural/functional aspects of these lectins. Moreover, the advances of techniques applied in protein-carbohydrate recognition have provided important approaches in order to screen for possible biological targets. The present review describes the efforts over the past 35 years to elucidate SVgalLs, highlighting their structure and carbohydrate recognition function involved in envenomation pathophysiology and potential biomedical applications.

Indexed as

Antitumor activityBactericidal activityCarbohydrate recognition domainC-type lectinGalactoside-binding proteinGlycoconjugatesInflammatory responseMitogenic activityPlatelet aggregationSnake venom

Identifiers

PMID26413085
PMCPMC4583214

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.