Evidence map›Paper›PMID 26412358›Full record

ReviewCurrent pharmaceutical design2015

Nano-Therapeutics for the Lung: State-of-the-Art and Future Perspectives.

Roshni Iyer, Connie C W Hsia, Kytai T Nguyen

Abstract readReview
In one paragraph

Review in Current pharmaceutical design, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Review
  3. Inhalable nanoparticle-based drug delivery system for non-small cell lung cancer therapy: promises and challenges.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2025
    Review
  4. Article
  5. Review
  6. Pulmonary drug delivery for acute respiratory distress syndrome.Pulmonary pharmacology & therapeutics · 2023
    Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Roshni Iyer
Connie C W Hsia
Kytai T NguyenDepartment of Bioengineering, University of Texas at Arlington, 500 UTA Blvd, ERB 241, Arlington, TX 76019. knguyen@uta.edu.

Funding

Signals for Post-pneumonectomy Compensatory Lung GrowthR01HL040070 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI HSIA, CONNIE C. W. · 1988 to 2014
$5.3M
Nanoparticle Drug Delivery in Post-Pneumonectomy Compensatory Lung GrowthU01HL111146 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI HSIA, CONNIE C. W., NGUYEN, KYTAI TRUONG · 2012 to 2016
$3.2M
Novel Engineered Particle Platform for Endothelium RegenerationR01HL118498 · NHLBI · UNIVERSITY OF TEXAS ARLINGTON · PI NGUYEN, KYTAI TRUONG, YANG, JIAN · 2014 to 2017
$1.5M
NHLBI NIH HHS R01 HL040070NHLBI NIH HHS R01 HL118498NHLBI NIH HHS R01 HL40070NHLBI NIH HHS U01 HL111146
6 · The paper itself

Abstract

Inhalation of aerosolized compounds is a popular, non-invasive route for the targeted delivery of therapeutic molecules to the lung. Various types of nanoparticles have been used as carriers to facilitate drug uptake and intracellular action in order to treat lung diseases and/or to facilitate lung repair and growth. These include polymeric nanoparticles, liposomes, and dendrimers, among many others. In addition, nanoparticles are sometimes used in combination with small molecules, cytokines, growth factors, and/or pluripotent stem cells. Here we review the rationale and state-of-the-art nanotechnology for pulmonary drug delivery, with particular attention to new technological developments and approaches as well as the challenges associated with them, the emerging advances, and opportunities for future development in this field.

Indexed as

Drug Delivery SystemsNanoparticlesAdministration, InhalationAerosolsAnimalsDendrimersDrug CarriersHumansLiposomesLungLung DiseasesNanotechnologyPolymersTissue DistributionAerosolsDendrimersDrug CarriersLiposomesPolymers

Identifiers

PMID26412358
PMCPMC4739652

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.