ReviewCurrent neuropharmacology2015
Pharmacology of Ultrasonic Vocalizations in adult Rats: Significance, Call Classification and Neural Substrate.
Review in Current neuropharmacology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
62 citing papers in PubMed, 139 citations in OpenAlex.
- Preserved social development but impaired executive function in aResearch square · 2026Article
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- Interrogating roles for VTA dopamine neurons in locomotion and ultrasonic vocalizations elicited by different classes of rewarding drugs.Psychopharmacology · 2026Article
- Effect of cannabinol, tetrahydrocannabivarin and cannabidiol on voluntary alcohol consumption.Alcohol and alcoholism (Oxford, Oxfordshire) · 2026Article
- Shelved cages impact affective behavior in Sprague Dawley rats - implications for animal welfare.Laboratory animals · 2026Article
- Humans correctly assign emotional valence of rat vocalizations.Frontiers in psychology · 2026Article
- Balancing consistency and flexibility: exploring trait and state optimism in rats using the cognitive judgement bias test.Frontiers in veterinary science · 2026Article
- Alternating self-administration sessions of cocaine and heroin impact drug-related motivation and vocalisations in rats.Psychopharmacology · 2025Article
- Frequent vocalizations and deep brain stimulation-responsive hyperkinesia in a striatal disinhibition rat model for Tourette syndrome.The international journal of neuropsychopharmacology · 2025Article
- Rearing in a Shelved Environment Chronically Modifies Offspring Behaviour and Physiology.The European journal of neuroscience · 2025Article
- The role of ultrasonic vocalizations in rat laryngological investigations.Physiology & behavior · 2025Review
- What do ultrasound vocalizations really mean in rats with different origins of pain?Pain reports · 2025Article
- Juvenile male rats form preferences based on strain when playing in groups but not in pairs.Frontiers in behavioral neuroscience · 2025Article
- Dorsal column pathway is involved in tactile reward-induced affective 50-kHz ultrasonic vocalizations in rats.PloS one · 2025Article
- Kappa-opioid receptor antagonism in the nucleus accumbens shell distinguishes escalated alcohol consumption and negative affective-like behavior from physiological withdrawal in alcohol-dependence.Pharmacology, biochemistry, and behavior · 2024Article
- Acoustic complexity of pup isolation calls in Mongolian hamsters: 3-frequency phenomena and chaos.Current zoology · 2024Article
- Species recognition and the divergences in the chemical and ultrasonic signals between two coexistingCurrent zoology · 2024Article
- Disentangling developmental effects of play aspects in rat rough-and-tumble play.Biology letters · 2024Article
- Rats that learn to vocalize for food reward emit longer and louder appetitive calls and fewer short aversive calls.PloS one · 2024Review
- Utilizing vocalizations to gain insight into the affective states of non-human mammals.Frontiers in veterinary science · 2024Review
2 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pharmacological studies of emotional arousal and initiation of emotional states in rats measured by their ultrasonic vocalizations are reviewed. It is postulated that emission of vocalizations is an inseparable feature of emotional states and it evolved from mother-infant interaction. Positive emotional states are associated with emission of 50 kHz vocalizations that could be induced by rewarding situations and dopaminergic activation of the nucleus accumbens and are mediated by D1, D2, and partially D3 dopamine receptors. Three biologically significant subtypes of 50 kHz vocalizations have been identified, all expressing positive emotional states: (1) flat calls without frequency modulation that serve as contact calls during social interactions; (2) frequencymodulated calls without trills that signal rewarding and significantly motivated situation; and (3) frequency-modulated calls with trills or trills themselves that are emitted in highly emotional situations associated with intensive affective state. Negative emotional states are associated with emission of 22 kHz vocalizations that could be induced by aversive situations, muscarinic cholinergic activation of limbic areas of medial diencephalon and forebrain, and are mediated by M2 muscarinic receptors. Two biologically significant subtypes of 22 kHz vocalizations have been identified, both expressing negative emotional sates: (1) long calls that serve as alarm calls and signal external danger; and (2) short calls that express a state of discomfort without external danger. The positive and negative states with emission of vocalizations are initiated by two ascending reticular activating subsystems: the mesolimbic dopaminergic subsystem as a specific positive arousal system, and the mesolimbic cholinergic subsystem as a specific negative arousal system.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.