Evidence map›Paper›PMID 26411560›Full record

ArticleJournal of tropical pediatrics2016

Hematological Indices at Birth of Infants of HIV-Positive Mothers Participating in a Prevention of Mother-to-Child Transmission Program.

Ijeoma Obumneme-Anyim, Ngozi Ibeziako, Ifeoma Emodi, Anthony Ikefuna, Tagbo Oguonu

Abstract read
In one paragraph

Article in Journal of tropical pediatrics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ijeoma Obumneme-AnyimDepartment of Paediatrics, University of Nigeria Teaching Hospital, Ituku-Ozalla Enugu, 402139, Nigeria, Enugu Campus, drijoms@yahoo.com.
Ngozi IbeziakoDepartment of Paediatrics, University of Nigeria Teaching Hospital, Ituku-Ozalla Enugu, 402139, Nigeria, Enugu Campus.
Ifeoma EmodiDepartment of Paediatrics, College of Medicine, University of Nigeria, Enugu, 400241, Nigeria.
Anthony IkefunaDepartment of Paediatrics, College of Medicine, University of Nigeria, Enugu, 400241, Nigeria.
Tagbo OguonuDepartment of Paediatrics, College of Medicine, University of Nigeria, Enugu, 400241, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe mother-to-child transmission of HIV, which accounts for 90% of infections in children, has been reduced markedly through the use of antiretroviral drugs by pregnant women and their newborns. Changes to the World Health Organization guidelines support further extension of the prevention of mother-to-child transmission programs with increased risk of toxicity on the fetuses.

aimTo determine the hematological indices at birth of infants exposed in utero to maternal antiretroviral drugs.

methodA comparative analytical study of 126 neonates whose blood samples were analyzed to determine their hematological indices.

resultThe hemoglobin, hematocrit, the total white blood cell (WBC) count and absolute neutrophil count (ANC) were significantly lower in infants of HIV-positive mothers. The total WBC and ANC were also significantly lower in the highly active antiretroviral therapy. HAART group and those exposed to maternal drugs for <1 year.

conclusionThere are significant changes in the hematological indices of infants of HIV-positive mothers at birth.

Indexed as

AdolescentAdultAnti-HIV AgentsAntiretroviral Therapy, Highly ActiveBlood Cell CountCase-Control StudiesFemaleFollow-Up StudiesHematocritHematologic TestsHemoglobinsHIV-1HIV InfectionsHumansInfantInfant, NewbornAnti-HIV AgentsHemoglobinsbirthhematological indicesHIV-infected mothersinfants

Identifiers

PMID26411560
PMCPMC4892384

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