Evidence map›Paper›PMID 26410804›Full record

ArticleInternational journal of surgery case reports2015

A rare case of Wunderlich syndrome five days after left hemicolectomy for colorectal cancer.

Michele Grassia, Angela Romano, Giuseppe Esposito, Bartolomeo Braccio, Modestino Pezzella, Amalia Rosaria Rita Rossetti, Francesco Torelli, Giuseppe Izzo, Roberto Alfano, Natale Di Martino

Open access · goldAbstract read
In one paragraph

Article in International journal of surgery case reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 6 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Michele GrassiaDepartment of General Surgery, Second University of Naples, Italy. Electronic address: michelegrassia@live.it.
Angela RomanoDepartment of General Surgery, Second University of Naples, Italy. Electronic address: angelaromano_ar@libero.it.
Giuseppe EspositoDepartment of General Surgery, Second University of Naples, Italy. Electronic address: g-expo@libero.it.
Bartolomeo BraccioDepartment of General Surgery, Second University of Naples, Italy. Electronic address: braccio.bartolomeo@email.it.
Modestino PezzellaDepartment of General Surgery, Second University of Naples, Italy. Electronic address: ninopezze@gmail.com.
Amalia Rosaria Rita RossettiDepartment of General Surgery, Second University of Naples, Italy. Electronic address: amaliarosariarita.rossetti@gmail.com.
Francesco TorelliDepartment of General Surgery, Second University of Naples, Italy. Electronic address: francesco.torelli@unina2.it.
Giuseppe IzzoDepartment of General Surgery, Second University of Naples, Italy. Electronic address: giuseppe.izzo@unina2.it.
Roberto AlfanoDepartment of General Surgery, Second University of Naples, Italy. Electronic address: roberto.alfano@unina2.it.
Natale Di MartinoDepartment of General Surgery, Second University of Naples, Italy. Electronic address: natale.dimartino@unina2.it.
University of Campania "Luigi Vanvitelli" · ITPegaso University · ITUniversity of Bari Aldo Moro · ITUniversity of Florence · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionWunderlich syndrome (WS) is a surgical emergency characterized by spontaneous, non-traumatic retroperitoneal hemorrhage. Angiomyolipoma (AML), a benign mesenchymal tumor, is the most frequent cause of WS. We present a case of WS, appearance five days after a left hemicolectomy for cancer. PRESENTATION OF CASE: A 66 years-old man with a sigmoid adenocarcinoma and a small left AML (3.4cm) was undergone to left hemicolectomy. He was subjected to bridging therapy with high doses of low-molecular-weight heparin for prosthetic replacement of heart valve secondary to endocarditis and atrial fibrillation. Five days after surgery he presents retroperitoneal hemorrhage due to rupture of AML diagnosed by a CT scan and scintigraphy with labeled red blood cells. Total left nephrectomy was performed as the patient became unstable. DISCUSSION: Rupture of a renal AML is the main cause of WS. This risk increases with the size of the tumor (>4cm) and during pregnancy. CT scan is the best imaging modalities for diagnosis. The bridging therapy increases the perioperative bleeding risk. These patients are conservative treated with selective transarterial embolization. Nephrectomy is limited for the patients hemodynamically unstable or in case of failed embolization.

conclusionThis is a unusual case of WS after surgery in patients with small AML and treated with high dose of anticoagulant for cardiac disease. There are no other similar cases in literature.

Indexed as

Angiomyolipoma (AML)Bridging therapyHemicolectomyNephrectomyWunderlich syndrome (WS)

Identifiers

PMID26410804
PMCPMC4643345
OpenAlexW1895298366

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.