ArticleJournal of neurology2015
Safety profile of intracranial electrode implantation for video-EEG recordings in drug-resistant focal epilepsy.
Article in Journal of neurology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.
- Determinants of diagnostic accuracy and therapeutic outcomes of SEEG in epilepsy: a systematic review.Neurosurgical review · 2025Pooled it
- Article
- Safety and efficacy of sEEG-guided resective surgery in patients with MRI-negative drug-resistant epilepsy.Neurosurgical review · 2026Article
- Sleep increases firing rate modulation during interictal epileptiform discharges in mesial temporal structures.Brain communications · 2026Article
- Implantation and reimplantation of intracranial EEG electrodes in patients considering epilepsy surgery.Epilepsia open · 2023Article
- The Role of Extra-Operative Cortical Stimulation and Mapping in the Surgical Management of Intracranial Gliomas.Brain sciences · 2022Article
- Visual Information Routes in the Posterior Dorsal and Ventral Face Network Studied with Intracranial Neurophysiology and White Matter Tract Endpoints.Cerebral cortex (New York, N.Y. : 1991) · 2022Article
- Delayed hemorrhage after pediatric stereo-electroencephalography: delayed occurrence or delayed diagnosis?Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2021Article
- Efficacy of a Second Brain Biopsy for Intracranial Lesions after Initial Negativity.Journal of clinical neurology (Seoul, Korea) · 2020Article
- Indications, Techniques, and Outcomes of Robot-Assisted Insular Stereo-Electro-Encephalography: A Review.Frontiers in neurology · 2020Review
- Stereoelectroencephalography in Pediatric Epilepsy Surgery.Journal of Korean Neurosurgical Society · 2019Article
- The Potential for a Speech Brain-Computer Interface Using Chronic Electrocorticography.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2019Review
- In-vivo measurements of human brain tissue conductivity using focal electrical current injection through intracerebral multicontact electrodes.Human brain mapping · 2017Article
- Major and minor complications in extraoperative electrocorticography: A review of a national database.Epilepsy research · 2016Article
- Emerging surgical therapies in the treatment of pediatric epilepsy.Translational pediatrics · 2016Review
Corrections and comments
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Authors and funding
12 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Invasive electroencephalography recordings with depth or subdural electrodes are necessary to identify the ictogenic area in some drug-resistant focal epilepsies. We aimed to analyze the safety profile of intracranial electrode implantation in a tertiary center and the factors associated with its complications. We retrospectively examined complications in 163 intracranial procedures performed in adult patients. Implantation methods included oblique depth stereotactic approach (n = 128) and medial-temporal depth stereotactic approach in combination with subdural strip placement (n = 35). 1201 depth macroelectrodes, 59 bundles of microelectrodes (in 30 patients) and 148 subdural electrodes were implanted. Complications were classified as major (requiring treatment or leading to neurological impairment) or minor. The rate of overall complications was 4.9% (n = 8), with 3.1% (n = 5) of major complications, though no permanent morbidity or mortality was recorded. Infection occurred in 1.2% and hemorrhage in 3.7% of patients. One hemorrhage occurred for every 225 electrodes implanted (4.4‰). Microelectrodes were not responsible for any complications. Overall and hemorrhagic complications were significantly associated with MRI-negative cases (7.3 and 6.3% versus 0%, p = 0.04). We believe that intracranial electrode implantation has a favorable safety profile, without permanent deficit. These risks should be balanced with the benefits of invasive exploration prior to surgery. Furthermore, this study provides preliminary evidence regarding the safety of micro-macroelectrodes.
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